Table 1.
Correlation between the clinicopathologic characteristics and miR-130b expression in HCC.
Characteristics | Total No. of Patients, n = 86 | No. of Patients | p | ||
---|---|---|---|---|---|
miR-130b high | miR-130b low | ||||
Age (year) | <50 | 36 | 19 | 17 | 0.323 |
≥50 | 50 | 21 | 29 | ||
Sex | Male | 65 | 28 | 37 | 0.261 |
Female | 21 | 12 | 9 | ||
HBV | Absent | 28 | 9 | 19 | 0.063 |
Present | 58 | 31 | 27 | ||
Serum AFP level (ng/mL) | <400 | 32 | 14 | 18 | 0.693 |
≥400 | 54 | 26 | 28 | ||
Tumor size (cm) | <5 | 32 | 16 | 16 | 0.618 |
≥5 | 54 | 24 | 30 | ||
No. of tumor nodules | 1 | 68 | 28 | 40 | 0.054 |
≥2 | 18 | 12 | 6 | ||
Cirrhosis | Absent | 36 | 13 | 23 | 0.101 |
Present | 50 | 27 | 23 | ||
Venous infiltration | Absent | 76 | 31 | 45 | 0.009 * |
Present | 10 | 9 | 1 | ||
Edmondson-Steiner grading | I + II | 65 | 25 | 40 | 0.008 * |
III + IV | 21 | 15 | 6 | ||
TNM tumor stage | I + II | 66 | 22 | 44 | <0.001 * |
III + IV | 20 | 18 | 2 |
HCC, hepatocellular carcinoma; HBV, hepatitis B virus; AFP, alpha-fetoprotein; TNM, tumor-node-metastasis; * Statistically significant.