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Degradation pathway of pentachlorophenol (PCP) in Sphingobium chlorophenolicum and 2,4,6-TCP in Cupriavidus necator. (A) PCP is converted to maleylacetate through a series of enzymatic transformations. PcpR is responsible for the transcriptional control of PcpA, PcpB and PcpE; and (B) 2,4,6-TCP is converted to maleylacetate through a series of enzymatic transformations. TcpR is responsible for the transcriptional control of TcpX, TcpA, TcpB, TcpC and TcpD.
