Table 2.

Summary of CoMFA and CoMSIA results.

Components	CoMFA	CoMSIA (SA)
q2 (r2cv)	0.636	0.843
r2ncv	0.988	0.989
SEE	0.094	0.096
F value	309.026	174.304
r2pred	0.658	0.601
No. of compounds	50	50
No. of optimal components	10	17
Contribution
Steric	0.671	0.677
Electrostatic	0.329	–
Hydrophobic	–	–
H-bond donor	–	–
H-bond acceptor	–	0.323