Table 2.
SNPs | Non-3 or 4 Grade Toxicity (11/12/22 †) | 3 or 4 Grade Toxicity (11/12/22) | MAF | Additive | Dominant | Recessive | ||||
---|---|---|---|---|---|---|---|---|---|---|
Non-3 or 4 Grade Toxicity | 3 or 4 Grade Toxicity | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | |||
rs16904853 | 83/152/75 | 26/51/11 | 0.49 | 0.41 | 0.74 (0.52–1.05) | 0.087 | 0.87 (0.52–1.47) | 0.607 | 0.45 (0.23–0.89) | 0.021 * |
rs2929970 | 123/145/47 | 34/49/5 | 0.38 | 0.34 | 0.82 (0.57–1.17) | 0.276 | 1.02 (0.63–1.65) | 0.944 | 0.34 (0.13–0.89) | 0.028 * |
rs2977549 | 58/136/124 | 7/45/36 | 0.40 | 0.34 | 0.78 (0.55–1.10) | 0.153 | 0.92 (0.57–1.49) | 0.745 | 0.39 (0.17–0.88) | 0.024 * |
rs2977551 | 122/142/52 | 38/44/7 | 0.39 | 0.33 | 0.76 (0.54–1.08) | 0.128 | 0.84 (0.52–1.36) | 0.486 | 0.43 (0.19–0.99) | 0.048 * |
† Wild-type/heterozygote/homozygote; * p < 0.05.