Skip to main content
. 2014 Nov 14;15(11):21011–21027. doi: 10.3390/ijms151121011

Table 2.

Association of rs16904853, rs2929970, rs2977549 and rs2977551 with hematologic toxicity in lung cancer patients.

SNPs Non-3 or 4 Grade Toxicity (11/12/22 ) 3 or 4 Grade Toxicity (11/12/22) MAF Additive Dominant Recessive
Non-3 or 4 Grade Toxicity 3 or 4 Grade Toxicity OR (95% CI) p OR (95% CI) p OR (95% CI) p
rs16904853 83/152/75 26/51/11 0.49 0.41 0.74 (0.52–1.05) 0.087 0.87 (0.52–1.47) 0.607 0.45 (0.23–0.89) 0.021 *
rs2929970 123/145/47 34/49/5 0.38 0.34 0.82 (0.57–1.17) 0.276 1.02 (0.63–1.65) 0.944 0.34 (0.13–0.89) 0.028 *
rs2977549 58/136/124 7/45/36 0.40 0.34 0.78 (0.55–1.10) 0.153 0.92 (0.57–1.49) 0.745 0.39 (0.17–0.88) 0.024 *
rs2977551 122/142/52 38/44/7 0.39 0.33 0.76 (0.54–1.08) 0.128 0.84 (0.52–1.36) 0.486 0.43 (0.19–0.99) 0.048 *

Wild-type/heterozygote/homozygote; * p < 0.05.