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. 2014 Nov 14;15(11):21045–21068. doi: 10.3390/ijms151121045

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© 2014 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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The phylogenetic tree and the protein structure of bird type I IFN receptors. (a) The phylogenetic tree of type I IFN receptors. It was built by MEGA5 program with 1000 bootstrap replicates and based on the neighbor-joining method. Blue, orange, green, pink in the picture represent mammals, birds, reptiles and amphibians, fish, respectively; and (b) The structure of bird type I IFN receptors. IFNAR1 reference sequences: Gallus gallus [GenBank: AAU85361.1], Ficedula albicollis [GenBank: XP005037152.1], Taeniopygia guttata [GenBank: XP002189268.1], Homo sapiens [GenBank: NP000620.2], Mus musculus [GenBank: AAH43935.1], Alligator mississippiensis [GenBank: XP006259500.1], Oncorhynchus mykiss [GenBank: NP001117887.1]. IFNAR2 reference sequences: Gallus gallus [GenBank: AAD13677.1], Columba livia [GenBank: XP005511439.1], Ficedula albicollis [GenBank: XP005037150.1], Sus scrofa [GenBank: NP001191704.2], Chrysemys picta bellii [GenBank: XP005283981.1], Alligator mississippiensis [GenBank: XP006259497.1].