Table 3.

Associations between inorganic soluble chemical constituents, polyaromatic hydrocarbons (PAHs) and microbes in indoor and outdoor air PM separately and the inflammatory and cytotoxic response markers in mouse macrophages after exposure to three different doses of particles (50, 150 and 300 μg/ml) for 24 h

Indoor
		n	MTT	PI	SubG 1	TNFα	MIP2	n	MTT	PI	SubG 1	TNFα	MIP2
PC1	A1	24	.546**	.457*	0.302	.722**	.713**	24	.912**	.735**	−0.094	.892**	.921**
	Ca	24	.771**	.637**	.682**	.543**	.603**	24	.856**	.733**	0.209	.730**	.777**
	Fe	21	.640**	.548*	0.287	.884**	.830**	24	.901**	.719**	−0.104	.882**	.909**
	K	24	.809**	.777**	.737**	.488*	.499*	24	.785**	.726**	0.285	.590**	.597**
	Mg	24	.589**	.555**	.528**	.453*	.477*	24	.928**	.767**	−0.026	.887**	.915**
	Na	24	.661**	.646**	.599**	.484*	.514*	24	.888**	.645**	0.13	.651**	.695**
	Ni	24	.510*	.540**	.507*	0.306	0.307	24	.623**	.504*	0.369	0.307	0.311
PC2	SO4	24	0.273	.467*	.583**	−0.357	−0.298	24	−0.12	−0.164	0.403	.-543**	.-529**
	NO3	24	.776**	.886**	.831**	0.27	0.317	21	0.316	0.152	0.373	−0.001	0.122
	V	24	.636**	.667**	.756**	0.092	0.115	24	.567**	.407*	.499*	0.222	0.292
	Zn	24	.551**	.547**	.686**	0.082	0.143	24	.441*	.415*	.476*	0.116	0.139
	TotalPAH	24	0.344	.414	.623**	−0.326	−0.229	24	−0.269	.-435*	.475*	.-675**	.-610**
PC3	C1	24	.863**	.724**	.683**	.697**	.702**	24	.551**	0.306	0.115	.462*	.559**
	F	21	.927**	.888**	.777**	.665**	.656**	18	0.463	0.254	.553*	0.019	0.101
	Cu	24	.497*	.570**	.583**	0.184	0.211	24	.810**	.763**	0.299	.629**	.641**
PC4	Universal bacterial assay	24	.820**	.671**	.674**	.567**	.599**	24	.847**	.589**	−0.188	.831**	.843**
Other	Genotoxic PAH	24	0.25	0.326	.557**	.-423*	−0.332	24	−0.269	−0.392	.477*	.-685**	.-636**
	EU PAH	24	0.131	0.22	.497*	.-533**	.-444*	24	−0.316	−0.353	.489*	.-710**	.-683**
	Penicillium sp./Aspergillus sp.	24	.666**	.565**	.571**	.472*	.475*	24	.788**	.659**	−0.045	.778**	.792**
	Cladosporidium cladosprioides	24	.787**	.685**	.483*	.820**	.816**	21	.806**	.666**	0.197	.803**	.766**
	Streptomyces sp.	24	.550**	.650**	.609**	0.083	0.065	15	.700**	.621*	.668**	0.232	0.361
	Mycobacterium sp.	24	.843**	.701**	.682**	.597**	.623**	15	.879**	.900**	0.479	.957**	.982**

The values are Spearman correlation coefficients (ρ), (** p < 0.01, * p < 0.05).

Genotoxic PAH compounds according to WHO (1998).

EU PAH compounds according to the EU Directive 2014/107/EC.