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. 2014 Nov 25;11:60. doi: 10.1186/s12989-014-0060-6

Table 4.

Association between inorganic soluble chemical constituents, polyaromatic hydrocarbons (PAHs) and microbes in PM 10–2.5 and PM 2.5–0.2 size ranges separately and the inflammatory and cytotoxic response markers in mouse macrophages after exposure to three different doses of particles (50, 150 and 300 μg/ml) for 24 h

PM 10–2.5 PM 2.5–0.2
n MTT PI SubG 1 TNFα MIP2 n MTT PI SubG 1 TNFα MIP2
PC1 Al 24 .474* .435* 0.256 .776* .805** 24 .690** .577** 0.153 .661** .635**
Ca 24 .583** .503* .453* .687** .763** 24 .810** .673** .430* .623** .684**
Fe 21 0.612** .605** 0.396 .743** .714** 24 .444* 0.337 −0.043 .542** .471*
K 24 .784** .734** .564** .878** .875** 24 .667** .572** 0.316 .463* .489*
Mg 24 .525** .503* 0.329 .775** .810** 24 .863** .819** .425* .717** .754**
Na 24 .544** .498* 0.323 .740** .790** 24 .823** .649** 0.352 .613** .642**
Ni 24 .619** .560** 0.396 .806** .802** 24 .573** .438* 0.216 0.385 0.388
PC2 SO4 24 .695** .643** .668** 0.287 0.343 24 .711** .487* 0.332 .454* .463*
NO3 24 0.32 0.354 0.281 0.303 0.402 21 .606** .451* 0.399 0.248 0.264
V 24 .556** .536** .483* .465* .500* 24 .607** .454* .423* 0.244 0.29
Zn 24 .688** .593** .597** .648** .692** 24 .771** .657** .503* .501* .557**
TotalPAH 24 0.358 0.298 .519** 0.018 0.13 24 0.379 0.083 0.343 −0.064 −0.011
PC3 Cl 24 .444* 0.35 .553** 0.136 0.242 24 .776** .575** .453* .518** .586**
F 18 .889** .769** .957** 0.176 0.271 21 .775** .604** .548* 0.373 .457*
Cu 24 .624** .573** .423* .790** .806** 24 .751** .814** .502* .618** .654**
PC4 Universal bacterial assay 24 .921** .890** .781** .713** .680** 24 .634** 0.317 0.159 0.403 .494*
Other Genotoxic PAH 24 0.393 0.345 .538** 0.062 0.168 24 .406* 0.109 0.365 −0.038 0.017
EUPah 24 .414* 0.364 .609** −0.002 0.096 24 0.401 0.108 0.355 −0.02 0.034
Penicillium sp./Aspergillus sp 24 .786** .816** .737** .609** .611** 24 .503* 0.3 0.089 .429* .479*
Cladosporidium cladosprioid 24 .603** .729** 0.337 .857** .835** 21 .734** 0.416 0.294 .487* .497*
Streptomyces sp. 21 .765** .755** .832** 0.19 0.17 18 .571* .511* 0.302 0.42 0.437
Mycobacterium sp. 24 .878** .891** .733** .810** .814** 15 .654** .529* 0.504 0.474 .565*

The values are Spearman correlation coefficients (ρ), (** p < 0.01, * p < 0.05).

Genotoxic PAH compounds according to WHO (1998).

EU PAH compounds according to the EU Directive 2004/107/EC.