Table 1.
Transduction method | Transduction mechanism | Simultaneous multiple analyte detection
+++ |
Real-time capability
+++ |
Fabrication speed and customizability
+++ |
---|---|---|---|---|
Immunofluorescence | Fluorescent molecule specific binding | ++ | + | +++ |
Micro-cantilevers | Actuation during binding event | +++ | + | + |
Surface plasmon resonance | Adsorption or binding changes local index of refraction and resonance of surface plasmon waves | - | +++ | +++ |
Resonance energy transfer | Specific binding or interaction enables emission from and detection of target | ++ | +++ | + |
Impedance | Impedance of cell membrane measured | - | +++ | ++ |