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. 2014 Apr 24;4(2):111–136. doi: 10.3390/bios4020111

Table 1.

Selected transduction methods and rated performance measurements for biosensing.

Transduction method Transduction mechanism Simultaneous multiple analyte detection
+++
Real-time capability
+++
Fabrication speed and customizability
+++
Immunofluorescence Fluorescent molecule specific binding ++ + +++
Micro-cantilevers Actuation during binding event +++ + +
Surface plasmon resonance Adsorption or binding changes local index of refraction and resonance of surface plasmon waves - +++ +++
Resonance energy transfer Specific binding or interaction enables emission from and detection of target ++ +++ +
Impedance Impedance of cell membrane measured - +++ ++