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. 2014 Nov 30;14:218. doi: 10.1186/s12883-014-0218-8

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© Liao et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Brain MRI findings of three NMOSD patients and three MS patients. FLAIR MRI shows a (A) continuous linear ependymal lesion along the ventricle in a 29-year-old woman with NMOSD; (B) symmetrical hypothalamic lesion in an 18-year-old girl with NMOSD; and (C) typical symmetrical and continuous ependymal lesion around the periaqueductal area in a 17-year-old girl with NMOSD. T2-weighted image shows (D) ependymal dot lesions beside the ventricle in a 32-year-old woman with MS. FLAIR MRI shows (E) an asymmetric hypothalamic lesion in a 26-year-old woman with MS and (F) asymmetric ependymal dot lesions along the periaqueductal gray in a 37-year-old woman with MS. NMOSD: neuromyelitis optica spectrum disorder; MS: multiple sclerosis; FLAIR: fluid attenuated inversion recovery; MRI: magnetic resonance imaging. NMOSD: neuromyelitis optica spectrum disorder.