Table 3.

Diagnosis of NMOSD using different MRI criteria

	Sensitivity	Specificity	Positive predictive value	Negative predictive value
1. Linear ependymal lesions	24% (6/25)	100% (29/29)	100%	60%
2. Unmet Matthews criteria*	40% (10/25)	79% (23/29)	63%	61%
3. 1 and 2	56% (14/25)	100% (29/29)	100%	73%

*The Matthews criteria used to separate MS from NMOSD: at least 1 lesion adjacent to the body of the lateral ventricle and in the inferior temporal lobe; or the presence of a subcortical U-fiber lesion or a Dawson’s finger-type lesion.

NMOSD: neuromyelitis optica spectrum disorder.