Table 1.
Characteristics of Subjects in the Pre-Post Group by Treatment Type
Water Treatment Groups | POE | POU | Comparison |
---|---|---|---|
General | |||
Subjects Per Water Treatment Group (n) | 16 | 8 | 5 |
Families Per Water Treatment Group (n) | 8 | 4 | 5 |
Race (% Caucasian) | 100 | 100 | 80 |
Sex (% Male) | 63 | 50 | 100 |
Age in Years, (Mean ± SE) | 31 ± 5 *† | 61 ± 3 * | 54 ± 4 |
Children < 18 Years Old (%) | 38 | 0 | 0 |
Weight in kg, (Mean ± SD) | 58 ± 8 † | 70 ± 5 | 83 ± 7 |
Any Tobacco Use During Study (%) | 6 | 0 | 0 |
Prior Water Ingestion Exposure (Mean ± SE) | |||
Well Water As (μg/L) | 40 ± 8 † | 45 ± 7 † | 1.1 ± 0.5 |
As Water Ingestion Reported (L/d) | 0.7 ± 0.1 * | 1.5 ± 0.4 * | 1.3 ± 0.6 |
Years of Exposure | 6.8 ± 1.2 * | 27.0 ± 6.1 *† | 7 ± 5 |
Cumulative As Ingestion Dose (mg) | 65 ± 19 *† | 482 ± 122 *† | 3 ± 2 |
Ingestion Dose per Body Weight (mg/kg) | 1.3 ± 0.5 *† | 7.0 ± 1.8 *† | 0.05 ± 0.03 |
Dermal Exposure (Mean ± SE) | |||
Showers per Week at Home | 5.1 ± 0.7 | 6.4 ± 0.6 | 6.6 ± 0.5 |
Baths in per Week at Home | 0.8 ± 0.4 | 0.03 ± 0.03 | 0 ± 0 |
Teeth Brushing per Week at Home | 10.8 ± 1.1 † | 14.0 ± 1.3 | 14.4 ± 0.4 |
Pool Use per Week During Season | 0.4 ± 0.3 | 0.4 ± 0.3 | 1.9 ± 1.4 |
Dietary Exposure (Mean ± SE) | |||
Seafood and Fish Meals per Week | 1.1 ± 0.2 | 1.8 ± 0.4 | 1.5 ± 0.4 |
Mushrooms with Meals per Week | 0.5 ± 0.3 | 0.3 ± 0.2 | 0.3 ± 0.1 |
Rice with Meals per Week | 1.5 ± 0.2 * | 0.5 ± 0.2 * | 2.0 ± 1.3 |
Poultry with Meals per Week | 2.6 ± 0.4 | 1.6 ± 0.4 | 2.8 ± 0.6 |
Urine Biomonitoring (Mean ± SE) | |||
Creatinine (g/L) | 1.6 ± 0.1 | 1.5 ± 0.2 | 1.8 ± 0.2 |
Arsenic in Urine (Geometric Mean ± SE) | |||
Initial Inorganic-Related As (μg/g creatinine) | 9.0 ± 1.9 †# | 14.8 ± 4.8 †# | 1.5 ± 0.4 |
Inorganic-Related As at Nine-Months (μg/g creatinine) | 3.4 ± 0.5 †# | 2.8 ± 1.4 # | |
Inorganic-Related As Reduction (Mean μg/g creatinine) | 7.3 ± 2.1 | 13.8 ± 4.9 | |
ANCOVA Adjusted As in Urinea (Est. Mean ± SE) | |||
Inorganic-Related As at Nine-Months (μg/g creatinine) | 2.6 ± 0.7 * | 7.0 ± 1.2 * | |
GEE Adjusted As in Urinea (Estimated Mean ± SE) | |||
Inorganic-Related As at Nine-Months (μg/g creatinine) | 2.5 ± 0.6 * | 7.2 ± 0.8 * | |
Inorganic-Related As Reduction (μg/g creatinine) | 10.2 ± 0.4 * | 8.1 ± 0.9 * |
p < 0.05, significant difference between POE and POU.
p < 0.05, significant difference from Control.
p < 0.05, significant difference within group between initial and final concentration.
Inorganic-related arsenic in final urine adjusted for propensity score and family correlation in GEE.
Comparison subjects provided only one urine sample.