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Comparison of selected CNA events (copy number losses) from reported literature (adapted from Hogan et al, Blood 2011)14
| Gene | Yang et al, Blood 200826 and Hogan et al. Blood, 201114 n=76 |
Mullighan et al. Science, 200822 n=47 |
Mullighan et al. Nature, 200729 n=192 |
|---|---|---|---|
| CDKN2A/B | 42.1% | 36.20% | 33.90% |
| IKZF1 | 38.2% | 25.50% | 8.90% |
| VPREB1 | 35.5% | N/A | N/A |
| PAX5 | 28.9% | 25.50% | 29.70% |
| EBF1 | 15.8% | 4.20% | 4.20% |
| MSH6 | 6.6% | None | None |
| TBL1XR1 | 9.2% | 10.60% | 3.60% |
| BTG1 | 15.8% | 2.10% | 6.70% |
| NR3C1 | 3.9% | 8.50% | 4.70% |
