Figure 4.

Progesterone levels are lower in protease inhibitor (PI)–exposed human immunodeficiency virus (HIV)–infected pregnant women and correlated with birth weight percentile. A, Plasma progesterone assessed by enzyme immunoassay in plasma specimens obtained during gestational weeks (GW) 25–28 from 17 HIV-negative and 27 HIV-infected pregnant women. B, Progesterone levels in 22 HIV-infected women receiving PI-based combination antiretroviral therapy (cART) and 5 receiving nonnucleoside reverse transcriptase inhibitor (NNRTI)–based cART. C, Correlation between birth weight percentile and progesterone levels in 22 HIV-infected women receiving PI-based cART. All data are shown as scatterplots with median values. Statistical comparisons were made using the Mann–Whitney test. Correlation was assessed by Spearman r.