Table 1.
Activity profile of the compounds under study.
| |||
|---|---|---|---|
| ID | Compound | IC50 (μM, Ishikawa) | pIC50 (Ishikawa) |
| 1 |
|
1.41 | 5.8500 |
| 2 |
|
0.91 | 6.0402 |
| 3 |
|
0.74 | 6.1286 |
| 4 |
|
2.13 | 5.6722 |
| 5 |
|
1.65 | 5.7819 |
| 6 |
|
2.54 | 5.5939 |
| 7 |
|
30.60 | 4.5127 |
| 8 |
|
1.56 | 5.8066 |
| 9 |
|
23.09 | 4.6366 |
| 10 |
|
28.23 | 4.5494 |
| 11 |
|
3.11 | 5.5068 |
| 12 |
|
19.53 | 4.7092 |
| 13 |
|
29.09 | 4.5372 |
| 14 |
|
26.68 | 4.5739 |
| 15 |
|
29.24 | 4.5338 |
| 16 |
|
2.93 | 5.5337 |
| 17 |
|
3.19 | 5.4956 |
| 18 |
|
33.78 | 4.4712 |
| 19 |
|
22.11 | 4.6554 |
| 20 |
|
20.41 | 4.6900 |
| 21 |
|
33.49 | 4.4750 |
| 22 |
|
0.36 | 6.4435 |
| 23 |
|
1.92 | 5.7153 |
| 24 |
|
>100 | >100 |
| TAM |
|
22.92 | 4.64 |