Table 7. Non-synonymous mutations in the RT region of Palestinian D3 subgenotypes.
nt position | aa position | Reported Function/detected in | Reference |
532:T/C | Y135H | Unknown/naïve patients | [69] |
562:C/A | L145M | Unknown/naïve patients | [70] |
616:A/G | I163V | Unknown | [71] |
766:T/A | S213T | Candidate mutation associated with hepatocellular carcinoma | [74] |
770:T/A | V214D | Unknown/naïve patient | GenBank:FJ904404 |
895:T/A | C256S | Unknown | [71] |
926:T/A | I266K | Unknown/patients treated with NRTIs | [68] |
Positions of the nucleotide (nt) mutation and the correlating amino acid (aa) are presented based on their location in the archived GenBank reference JF754625. Corresponding references and proposed functions are provided in the last two columns. NRTIs: nucleoside and/or nucleotide reverse-transcriptase inhibitors.