Table 2. Ranking of gene expression markers according to the highest fold change in symptomatic (S) compared with asymptomatic (A) samples quantified by real time RT−PCR.
| Gene name | FC (S vs A) | P-value |
| TIMP metallopeptidase inhibitor 1 (TIMP1) | 3.45 | 0.032* |
| Inositol 1,4,5-triphosphate repector, type 1 (ITPR1) | 2.83 | 0.037* |
| Heme oxygenase (decycling) 1 (HMOX1) | 2.07 | 0.065 |
| CD163 molecule/Hemoglobin scavenger receptor (CD163) | 1.81 | 0.044* |
| Mitogen-activated protein kinase 1 (MAPK1) | 1.75 | 0.057 |
| Endoplasmic reticulum protein 29 (ERP29) | 1.68 | 0.031* |
| Mesencephalic astrocyte-derived neurotrophic factor (MANF) | 1.68 | 0.48 |
| Eva-1 homolog A (C. Elegans) (EVA1A) | 1.57 | 0.033* |
| Transforming growth factor, beta 1 (TGFB1) | 1.57 | 0.13 |
| Parkinson protein 2, E3 ubiquitin protein ligase (PARK2) | 1.52 | 0.043* |
| Protein disulfide isomerase family A, member 6 (PDIA6) | 1.47 | 0.093 |
| Collagen, type III, alpha 1 (COL3A1) | 1.42 | 0.063 |
| Matrix metallopeptidase 9 (gelatinase B) (MMP9) | 1.4 | 0.05* |
The statistical significance was analyzed with the non-parametrical statistical test Mann-Whitney U test (* P≤0.05 and ** P≤0.0001).