Table 3. Ranking of gene expression markers according to highest fold change in asymptomatic (A) compared with symptomatic (S) samples quantified by Real Time RT−PCR.
Gene name | FC (A vs S) | P-value |
Microtubule-associated protein 1 light chain 3 beta (MAP1LC3B) | 5 | <0.0001** |
Endoplasmic reticulum protein 27 (ERP27) | 4.07 | 0.047* |
Interleukin 12B (IL12B) | 2.5 | 0.028* |
Lectin, mannose-binding, 1 (LMAN1) | 2 | 0.04* |
RAB24, member RAS oncogene family (RAB24) | 1.75 | 0.031* |
ERO1-like beta (S.cerevisiae) (ERO1LB) | 1.67 | 0.034* |
v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1) | 1.67 | 0.074 |
Protein disulfide isomerase family A, member 4 (PDIA4) | 1.52 | 0.062 |
SEC63 homolog (S. cerevisiae) (SEC63) | 1.46 | 0.05* |
Heat shock 70 kDa protein 1A (HSPA1A) | 1.46 | 0.024* |
Stress-associated endoplasmic reticulum protein 1 (SERP1) | 1.4 | 0.32 |
DnaJ (Hsp40) homolog, subfamily B, member 9 (DNAJB9) | 1.4 | 0.067 |
The statistical significance was analyzed with the non-parametrical statistical test Mann-Whitney U test (* P≤0.05 and ** P≤0.0001).