Table 2.
Clinical outcome of tacrolimus to sirolimus conversion (n = 5)
| Parameter | Pre-conversion | Post-conversion | P value |
|---|---|---|---|
| Complete blood count | |||
| White blood cell (103/µl) | 5·9 ± 2·9 | 6·1 ± 2·6 | 0·66 |
| Haemoglobin (g/dl) | 14·4 ± 1·8 | 13·9 ± 1·9 | 0·13 |
| Platelet (103/µl) | 212·8 ± 29·6 | 221·0 ± 31·5 | 0·17 |
| BUN (mg/dl) | 16·1 ± 3·3 | 14·9 ± 2·8 | 0·51 |
| Serum creatinine (mg/dl) | 1·47 ± 0·28 | 1·47 ± 0·34 | 0·93 |
| eGFR by MDRD (ml/min/1·73 m2) | 58·7 ± 13·8 | 59·9 ± 16·0 | 0·76 |
| Urine protein/urine creatinine | 0·05 ± 0·04 | 0·06 ± 0·03 | 0·65 |
| Mean trough SRL level (ng/ml) | – | 6·4 ± 2·5 | – |
BUN, blood urea nitrogen; eGFR, estimated glomerular filtration rate; MDRD, modified diet renal disease.