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. 2014 Dec 8;144(1):107–115. doi: 10.1111/imm.12355

Figure 5.

Figure 5

Effect of anti-IgE monoclonal antibody (mAb) on IgE-mediated cytokine production at the seventh challenge. Anti-IgE mAb was intraperitoneally administered on day 7 [OE-1 (7th) + anti-IgE mAb]. Negative and positive controls were non-sensitized–challenged [NS-C (7th)] and OE-1-sensitized, rat IgG1 mAb-treated [OE-1 (7th) + rat IgG1] mice, respectively. Interleukin-4 (IL-4) (a), IL-5 (b), IL-13 (c), IL-17A (d), IL-33 (e), and CXCL1 (f) from the lung homogenate obtained 24 hr after the seventh challenge were measured. Each value is the mean ± SEM of four to seven animals from two separate experiments. *P < 0·05 compared with OE-1 (7th) + rat IgG1 group.