Figure 3.
Mean annualized rates of change in right prefrontal cortex thickness and third ventricle volume by duration of prodromal symptoms. Group differences were significant for both variables (F=9.68, p=0.0000002 for right prefrontal cortex; F=3.87, p=0.004 for third ventricle). Converters with short durations showed significantly steeper reduction in right prefrontal thickness compared with long-duration converters, short- and long-duration non-converters, and controls; they also showed significantly greater third ventricle expansion compared with all of the groups except for long-duration converters. Converters with long durations showed significantly steeper reduction in right prefrontal thickness and significantly greater expansion of the third ventricle compared with long-duration non-converters and controls.