Table 1.
Demographic and clinical characteristics
| Demographic characteristics | L-PANSS (n=80) | H-PANSS (n=9) | P value |
|---|---|---|---|
| Age (years) | 35 ± 9.3 | 37 ± 9.6 | 0.801 |
| Male/Female(male percentage) | 2/6 (25%) | 4/5 (44%) | 0.434 |
| Duration of education (years) | 13.0 ± 3.3 | 11.6 ± 3.6 | 0.405 |
| Age at illness onset (years) (years) | 25.1 ± 7.5 | 22.3 ± 7.4 | 0.453 |
| Duration of illness (months) | 101.5 ± 71.8 | 186.7 ± 63.8 | 0.021 * |
| Clinical psychiatric condition rating scales | |||
| Clinical Global Impression (CGI) | 2.9 ± 0.4 | 3.7 ± 0.5 | 0.002 ** |
| Quality of life scale (QLS) | 63.3 ± 11.4 | 35.4 ± 14.0 | < 0.001** |
| Hamilton Depression Rating scale | 8.1 ± 5.2 | 12.7 ± 8.4 | 0.207 |
| Medication amount | |||
| Chlorpromazine equivalents | 212.5 ± 64.1 | 237.2 ± 91.0 | 0.532 |
| Diazepam equivalents | 12.5 ± 16.9 | 5.0 ± 6.1 | 0.232 |
| Extra-pyramidal symptoms rating scales | |||
| Abnormal Involuntary Movement scale | 4.1 ± 6.3 | 5.11 ± 4.5 | 0.712 |
| Barnes Akathisia Rating scale | 0.6 ± 1.2 | 2.1 ± 2.6 | 0.162 |
| Simpson-Angus scale | 5.8 ± 4.7 | 7.3 ± 3.5 | 0.440 |
All data were expressed as mean value ± standard deviation, except gender.
Low-PANSS (L-PANSS) group included schizophrenics with Positive and Negative Syndrome Scale (PANSS) total score below 65 (median of PANSS total scores of all 17 subjects); High-PANSS (H-PANSS) group included those with PANSS total scores 65 or higher.
*:P<0.05 and **:P<0.01, significance between groups.