Figure 1.

Thyroid tumors and mutational profile. PTEN, phosphatase and tensin homolog.

BRAF, b-type rapidly accelerated fibrosarcoma;RAS, rat sarcoma; RET/PTC, rearranged during transfection/papillary thyroid carcinoma; PI3KCA, phosphatidylinositol 3-kinase oncogene; TRK, receptor thyrosine kinase; PAX8/PPAR, paired box 8/peroxisome proliferator-activated receptor gamma; PTEN, phosphatase and tensin homolog; TP53, tumor protein p53; CTNNB1, catenin (cadherin-associated protein beta 1); AKT1, v-akt murine thymoma viral oncogene homolog 1;RET, rearranged during transfection.