Table 2.
Effects of MMA on Commonly Used Chemotherapy Drugs
| Drug | Typical Daily Dose Reimbursement ($) |
Difference ($) | |
|---|---|---|---|
| 2004 | 2005 | ||
| Leucovorin | 48.00 | 20.77 | −27.23 |
| Bevacizumab | 4,571.70 | 3,996.84 | −574.86 |
| Carboplatin injection | 1,521.96 | 839.05 | −682.91 |
| Cetuximab | 10,177.92 | 9,239.13 | −938.79 |
| Cisplatin | 257.64 | 67.65 | −189.99 |
| Cyclophosphamide | 71.82 | 15.82 | −56.00 |
| Docetaxel | 2,109.80 | 2,068.81 | −40.99 |
| Etoposide | 102.51 | 33.84 | −68.68 |
| Fluorouracil | 38.85 | 29.30 | −9.56 |
| Gemcitabine | 2,853.20 | 3,232.33 | 379.13 |
| Irinotecan | 4,172.82 | 4,302.11 | 129.29 |
| Oxaliplatin | 4,495.40 | 4,430.36 | −65.04 |
| Paclitaxel | 1,244.52 | 134.55 | −1,109.97 |
| Pemetrexed | 4,306.83 | 3,771.06 | −535.77 |
| Topotecan | 2,824.68 | 2,994.61 | 169.93 |
| Vinorelbine | 685.71 | 476.90 | −208.81 |
| Doxorubicin | 89.76 | 58.84 | −30.92 |
| Doxorubicin liposome | 3,168.54 | 3,245.61 | 77.07 |
| Trastuzumab | 2,912.56 | 3,000.20 | 87.64 |
| Ifosfomide | 1,210.95 | 429.27 | −781.68 |
| Mitomycin | 185.64 | 77.30 | −108.34 |
NOTE. Dollar amounts are for a daily dose, not a full multiday regimen.
Abbreviation: MMA, Medicare Prescription Drug, Improvement, and Modernization Act of 2003.