Suggested list of potential immune-mediated disorders of interest (reproduced from Tavares Da Silva et al.¹⁴)^*

Neuro-inflammatory disorders	Musculoskeletal disorders	Skin disorders
Cranial nerve inflammatory disorders, including paralyses/paresis (e.g. Bell's palsy)	Systemic lupus erythematosus	Psoriasis
Optic neuritis	Systemic sclerosis (with limited or diffuse cutaneous involvement)	Vitiligo
Multiple sclerosis	Dermatomyositis	Erythema nodosum
Transverse myelitis	Polymyositis	Autoimmune bullous skin diseases (including pemphigus, pemphigoid and dermatitis herpetiformis)
Acute disseminated encephalomyelitis including site-specific variants: encephalitis, encephalomyelitis, myelitis, myeloradiculoneuritis, cerebellitis	Anti-synthetase syndrome	Cutaneous lupus erythematosus
Myasthenia gravis (including Lambert–Eaton myasthenic syndrome)	Rheumatoid arthritis	Alopecia areata
Immune-mediated peripheral neuropathies and plexopathies (including Guillain–Barré syndrome, Miller Fisher syndrome and other variants: chronic inflammatory demyelinating polyneuropathy, multifocal motor neuropathy and polyneuropathies associated with monoclonal gammopathy)	Juvenile chronic arthritis (including Still's disease)	Lichen planus
Narcolepsy	Polymyalgia rheumatica	Sweet's syndrome
	Spondyloarthritis, including ankylosing spondylitis, reactive arthritis (Reiter's syndrome) and undifferentiated spondyloarthritis	Morphoea
	Psoriatic arthropathy
	Relapsing polychondritis
	Mixed connective tissue disorder
Liver disorders	Gastrointestinal disorders	Metabolic and endocrine disorders
Autoimmune hepatitis	Crohn's disease	Autoimmune thyroiditis (including Hashimoto thyroiditis)
Primary biliary cirrhosis	Ulcerative colitis	Grave's or Basedow's disease
Primary sclerosing cholangitis	Ulcerative proctitis	Diabetes mellitus type I
Autoimmune cholangitis	Celiac disease	Addison's disease
Vasculitides	Others
Large vessels vasculitis including giant cell arteritis such as Takayasu's arteritis and temporal arteritis	Autoimmune haemolytic anaemia
	Autoimmune thrombocytopenia
Medium sized and/or small vessels vasculitis including polyarteritis nodosa, Kawasaki's disease, microscopic polyangiitis, Wegener's granulomatosis, Churg–Strauss syndrome (allergic granulomatous angiitis), Buerger's disease (thromboangiitis obliterans), necrotizing vasculitis and anti-neutrophil cytoplasmic antibody (ANCA) positive vasculitis (type unspecified), Henoch–Schonlein purpura, Behcet's syndrome, leukocytoclastic vasculitis	Antiphospholipid syndrome
	Pernicious anaemia
	Autoimmune glomerulonephritis (including IgA nephropathy, glomerulonephritis rapidly progressive, membranous glomerulonephritis, membranoproliferative glomerulonephritis and mesangioproliferative glomerulonephritis)
	Uveitis
	Autoimmune myocarditis/cardiomyopathy
	Sarcoidosis
	Stevens–Johnson syndrome
	Sjögren's syndrome
	Idiopathic pulmonary fibrosis
	Goodpasture syndrome
	Raynaud's phenomenon

^*Note that this table is not intended to be exhaustive but is indicative of the type of conditions that could be included as adverse events of special interest in clinical trials.