Table 2.
Baseline | Post-treatment | Change from baseline | |||||
---|---|---|---|---|---|---|---|
Mean | SD | Mean | SD | Mean | SD | ||
Multi-tasking scorea | Placebo | 8596 | 2756 | 9228 | 3006 | 632 | 1003 |
25 g glucose | 8859 | 2436 | 9848 | 2538 | 989 | 1195 | |
60 g glucose | 8754 | 2654 | 9422 | 2528 | 668 | 1179 | |
Caffeine–glucose | 9530 | 2277 | 10 999 | 2470 | 1469 | 1538 | |
Mathematical reasoning score | Placebo | 484 | 289 | 530 | 315 | 63 | 117 |
25 g glucose | 369 | 150 | 377 | 168 | 8 | 101 | |
60 g glucose | 434 | 334 | 485 | 346 | 52 | 162 | |
Caffeine–glucose | 374 | 215 | 403 | 250 | 29 | 102 | |
Maths correct (number) | Placebo | 53 | 28 | 57 | 31 | 6 | 11 |
25 g glucose | 41 | 15 | 41 | 17 | 0 | 9 | |
60 g glucose | 51 | 27 | 55 | 28 | 5 | 16 | |
Caffeine–glucose | 42 | 20 | 45 | 23 | 3 | 10 | |
Maths errors (number) | Placebo | 4 | 4 | 4 | 4 | 0 | 3 |
25 g glucose | 4 | 4 | 4 | 2 | 0 | 4 | |
60 g glucose | 7 | 13 | 7 | 14 | −1 | 4 | |
Caffeine–glucose | 5 | 7 | 5 | 9 | 0 | 2 | |
Maths speeda (ms) | Placebo | 6047 | 3489 | 5208 | 2627 | −505 | 902 |
25 g glucose | 5537 | 1471 | 5266 | 1871 | −387 | 1256 | |
60 g glucose | 4762 | 1851 | 4558 | 1711 | −39 | 751 | |
Caffeine–glucose | 5512 | 2206 | 4712 | 1781 | −927 | 1270 | |
Stroop score | Placebo | 3431 | 1248 | 3588 | 1439 | 157 | 627 |
25 g glucose | 3730 | 1328 | 4182 | 1362 | 353 | 798 | |
60 g glucose | 3235 | 1154 | 3542 | 1187 | 307 | 813 | |
Caffeine–glucose | 3561 | 1144 | 3975 | 1207 | 414 | 875 | |
Stroop error (number) | Placebo | 1 | 2 | 2 | 3 | 1 | 3 |
25 g glucose | 2 | 2 | 3 | 3 | 1 | 3 | |
60 g glucose | 3 | 5 | 4 | 5 | 1 | 3 | |
Caffeine–glucose | 2 | 2 | 3 | 5 | 0 | 2 | |
Stroop speedb (ms) | Placebo | 1961 | 1462 | 1869 | 1624 | −135 | 238 |
25 g glucose | 1700 | 539 | 1587 | 566 | −86 | 228 | |
60 g glucose | 1715 | 1054 | 1647 | 1050 | −68 | 253 | |
Caffeine–glucose | 1761 | 770 | 1515 | 599 | −218 | 278 | |
Stroop misses (number) | Placebo | 27 | 13 | 27 | 14 | 0 | 4 |
25 g glucose | 26 | 11 | 25 | 12 | −1 | 7 | |
60 g glucose | 30 | 12 | 29 | 13 | −1 | 6 | |
Caffeine–glucose | 26 | 12 | 27 | 12 | 1 | 5 | |
Tracking score | Placebo | 429 | 59 | 415 | 80 | −14 | 86 |
25 g glucose | 378 | 130 | 288 | 533 | −5 | 74 | |
60 g glucose | 358 | 183 | 378 | 99 | −11 | 108 | |
Caffeine–glucose | 384 | 129 | 362 | 166 | −21 | 102 | |
Tracking timeouts (number) | Placebo | 36 | 41 | 46 | 66 | 2 | 48 |
25 g glucose | 71 | 94 | 151 | 493 | 1 | 55 | |
60 g glucose | 87 | 152 | 65 | 67 | 6 | 77 | |
Caffeine–glucose | 64 | 79 | 76 | 103 | 11 | 75 | |
Working memory score | Placebo | 4383 | 1863 | 5002 | 1989 | 619 | 1157 |
25 g glucose | 4728 | 1863 | 5017 | 1843 | 289 | 1092 | |
60 g glucose | 5212 | 2037 | 6260 | 2451 | 845 | 1344 | |
Caffeine–glucose | 4639 | 2006 | 5232 | 2280 | 515 | 1142 | |
Working memory responses (number) | Placebo | 504 | 232 | 559 | 264 | 43 | 93 |
25 g glucose | 518 | 217 | 590 | 228 | 71 | 121 | |
60 g glucose | 556 | 198 | 590 | 215 | 34 | 129 | |
Caffeine–glucose | 595 | 221 | 713 | 273 | 96 | 134 | |
Working memory errors (number) | Placebo | 20 | 28 | 26 | 39 | 4 | 10 |
25 g glucose | 21 | 24 | 27 | 30 | 6 | 13 | |
60 g glucose | 23 | 22 | 26 | 29 | 1 | 12 | |
Caffeine–glucose | 18 | 16 | 27 | 22 | 9 | 15 | |
Working memory timeouts (number) | Placebo | 38 | 15 | 36 | 15 | −1 | 7 |
25 g glucose | 38 | 12 | 35 | 16 | −3 | 8 | |
60 g glucose | 37 | 12 | 36 | 14 | −1 | 6 | |
Caffeine–glucose | 36 | 12 | 33 | 14 | −3 | 8 | |
Working memory speed (ms) | Placebo | 1695 | 1747 | 1600 | 1706 | −49 | 207 |
25 g glucose | 1366 | 661 | 1229 | 517 | −100 | 306 | |
60 g glucose | 1388 | 1199 | 1256 | 797 | −37 | 197 | |
Caffeine–glucose | 1251 | 669 | 1109 | 618 | −143 | 212 | |
Working memory list retrieves (number) | Placebo | 3 | 8 | 3 | 8 | 0 | 1 |
25 g glucose | 2 | 2 | 1 | 1 | 0 | 1 | |
60 g glucose | 1 | 1 | 1 | 1 | 0 | 1 | |
Caffeine–glucose | 2 | 3 | 1 | 2 | −1 | 1 |
Means with SDs are shown.
Significant main effect.
Trend towards a main effect of treatment on change-from-baseline scores.