Table 3.
Patient characteristics | Risk category | LDL-C target | Number of patients at baseline, n (%) | Patients achieving treatment goal, n (%) | Patients achieving treatment goal according to prescribed statin, n (%) [mean dose, mg ± SD] |
---|---|---|---|---|---|
All patients | All | 339 (32.5) |
Atorvastatin: 135 (28.1) [17.6 ± 10.2] Simvastatin: 46 (33.8) [22.0 ± 11.1] Rosuvastatin: 135 (39.0) [13.3 ± 4.7] Fluvastatin:4 (20.0) [NA] Pravastatin:3 (37.5) [NA] |
||
Established CVD plus diabetes, smoker, low HDL-C and high triglycerides, metabolic syndrome or multiple risk factors (see definition below) | Very high | <70 mg/dL (1.81 mmol/L) | 393 (37.7) | 42 (10.7) |
Rosuvastatin: 14 (11.4) [NA] Atorvastatin: 21 (10.4) [NA] Simvastatin: 4 (8.9) [NA] |
CHD, or CHD risk equivalents, or Framingham 10-year risk >20% | High | <100 mg/dL (2.59 mmol/L) | 362 (34.7) | 124 (34.2) |
Rosuvastatin: 46 (49.0) [NA] Atorvastatin: 53 (40.0) [NA] Simvastatin: 20 (45.6) [NA] |
>2 risk factors with Framingham 10-year risk between 10% and 20% | Medium high | <100 mg/dL (2.59 mmol/L) | 38 (3.6) | 3 (7.9) |
Rosuvastatin: 1 (9.1) [NA] Atorvastatin: 1 (6.2) [NA] Simvastatin: 1 (20.0) [NA] |
>2 risk factors with Framingham 10-year risk <10% | Medium low | <130 mg/dL (3.36 mmol/L) | 167 (16.0) | 111 (66.5) |
Rosuvastatin: 47 (78.2) [NA] Atorvastatin: 42 (65.6) [NA] Simvastatin: 14 (51.8) [NA] |
0–1 risk factor | Low | <160 mg/dL (4.14 mmol/L) | 83 (8.0) | 59 (71.1) |
Rosuvastatin: 27 (79.4) [NA] Atorvastatin: 18 (64.3) [NA] Simvastatin: 7 (58.3) [NA] |
CHD coronary heart disease, CVD cardiovascular disease, DBP diastolic blood pressure, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, NCEP ATP III National Cholesterol Education Program Adult Treatment Panel III, NA not available, SBP systolic blood pressure, SD standard deviation