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. 2013 Dec 2;23(3):240–250. doi: 10.1002/pds.3544

Treatment deviation in patients initiated on rosuvastatin 5 mg and simvastatin 20 mg, respectively

Type of first deviation from initial treatment during follow-up * Total Men Women
Rosuvastatin 5 mg Simvastatin 20 mg Rosuvastatin 5 mg Simvastatin 20 mg Rosuvastatin 5 mg Simvastatin 20 mg
n (%) n (%) n (%) n (%) n (%) n (%)
Change to another dose of the initial statin 7284 4825 3474 2129 3810 2696
(6.8) (8.5) (7.5) (8.5) (6.3) (8.5)
Switch to another statin 6101 4962 2631 2214 3470 2748
(5.7) (8.7) (5.7) (8.8) (5.7) (8.7)
Temporary discontinuation for more than 6 months 7825 4107 3241 1747 4584 2360
(7.3) (7.2) (7.0) (6.9) (7.6) (7.5)
Permanent discontinuation not preceded by switches or temporary discontinuation 20 409 10 303 8324 4256 12 085 6047
(19.1) (18.1) (18.0) (16.9) (19.9) (19.1)
All types 34 335 19 372 14 196 8217 20 139 11 155
(38.9) (42.5) (38.2) (41.0) (39.5) (43.8)
*

Between the end of the 1-year selection period with regular prescriptions for the initial treatment and the end of the study period.

Followed by a new prescription for statin (i.e., an interval of more than 6 months between two consecutive prescriptions).

Before the end of the study period (i.e., with an interval of more than one month between (1) the month at which the last prescription for the initial treatment should have ended and (2) the end of the study period).