Treatment deviation in patients initiated on rosuvastatin 5 mg and simvastatin 20 mg, respectively
Type of first deviation from initial treatment during follow-up * | Total | Men | Women | |||
---|---|---|---|---|---|---|
Rosuvastatin 5 mg | Simvastatin 20 mg | Rosuvastatin 5 mg | Simvastatin 20 mg | Rosuvastatin 5 mg | Simvastatin 20 mg | |
n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |
Change to another dose of the initial statin | 7284 | 4825 | 3474 | 2129 | 3810 | 2696 |
(6.8) | (8.5) | (7.5) | (8.5) | (6.3) | (8.5) | |
Switch to another statin | 6101 | 4962 | 2631 | 2214 | 3470 | 2748 |
(5.7) | (8.7) | (5.7) | (8.8) | (5.7) | (8.7) | |
Temporary discontinuation for more than 6 months † | 7825 | 4107 | 3241 | 1747 | 4584 | 2360 |
(7.3) | (7.2) | (7.0) | (6.9) | (7.6) | (7.5) | |
Permanent discontinuation not preceded by switches or temporary discontinuation ‡ | 20 409 | 10 303 | 8324 | 4256 | 12 085 | 6047 |
(19.1) | (18.1) | (18.0) | (16.9) | (19.9) | (19.1) | |
All types | 34 335 | 19 372 | 14 196 | 8217 | 20 139 | 11 155 |
(38.9) | (42.5) | (38.2) | (41.0) | (39.5) | (43.8) |
Between the end of the 1-year selection period with regular prescriptions for the initial treatment and the end of the study period.
Followed by a new prescription for statin (i.e., an interval of more than 6 months between two consecutive prescriptions).
Before the end of the study period (i.e., with an interval of more than one month between (1) the month at which the last prescription for the initial treatment should have ended and (2) the end of the study period).