Table 1.
The complete CYP105 proteins from Streptomyces listed on the Cytochrome P450 homepage (http://drnelson.uthsc.edu/CytochromeP450.html), with those mentioned in the text that have yet to be assigned within official P450 nomenclature included
| CYP105 | Uniprot ID | Species of Streptomyces | Function (if known) |
|---|---|---|---|
| A1 | P18326 | griseolus | Wide range (see text)*,† |
| A3 | Q59831 | carbophilus | Pravastatin synthesis† |
| B1 | P18327 | griseolus | Sulfonylurea oxidation* |
| B2 | Q595R4 | tubercidicus | Avermectin oxidation† |
| C1 | P23296 | sp. | |
| C- | A6YRR3 | virginiae | Steroid oxidation* |
| D1 | P26911 | griseus | Xenobiotic degradation* |
| D4 | O85697 | lividans | |
| D5 | Q9EWS4 | coelicolor | Fatty acids‡ |
| D6 | Q79ZT5 | avermitilis | Filipin C1′‡ |
| D7 | Q825I8 | avermitilis | Pentalenic acid, xenobiotics*,‡ |
| D8 | Q595S4 | tubercidicus strain I-1529 | Avermectin oxidation† |
| D9 | Q8KSY0 | sp. JP95 | Griseorhodin‡ |
| F1 | Q9X5P8 | lavendulae | Unknown polyketide |
| F2 | Q70AS0 | peucetius | Oleandomycin oxidation‡ |
| H1 | Q9L4W8 | noursei ATCC 11455 | Nystatin‡ |
| H3 | Q9EW94 | natalensis | Pimaricin‡ |
| H4 | Q93NX1 | nodosus | Amphotericin‡ |
| H5 | Q9EWC4 | griseus | Candidicin‡ |
| K1 | Q9X9P7 | tendae strain Tue901 | Nikkomycin‡ |
| K2 | Q8RNW8 | ansochromogenes | Nikkomycin‡ |
| L1 | Q9ZHQ1 | fradiae | Tylosin‡ |
| M1 | Q9KJ93 | clavuligerus | Clavulanic acid‡ |
| N1 | Q9EWP1 | coelicolor | Coelibactin‡ |
| N- | D6ESR2 | lividans | Putatively coelibactin‡ |
| N- | D9XRK0 | griseoflavus | Putatively coelibactin‡ |
| N- | G2NQM5 | SirexAA-E | Putatively coelibactin‡ |
| P1 | Q79ZT4 | avermitilis | Filipin C26‡ |
| P2 | Q70AS3 | peucetius | Flavone oxidation* |
| Q1 | Q82MP9 | avermitilis | |
| Q5 | C9Z4Z8 | scabies | |
| R1 | Q93HF0 | avermitilis | |
| U1 | Q84G11 | hygroscopicus strain NRRL3602 | Geldanamycin‡ |
| V1 | Q6V1N2 | sp. HK803 | Phoslactomycin‡ |
| Z1 | C9ZGE5 | scabies strain 87·22 | |
| AA1 | Q595R1 | tubercidicus strain R922 | Avermectin oxidation† |
| AA2 | Q595S0 | tubercidicus strain I-1529 | Avermectin oxidation† |
In the final column, *indicates a xenobiotic breakdown function, †a biotechnological use and ‡indicates the biosynthetic pathway the protein is associated with.