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. 2014 Nov 23;2014:210469. doi: 10.1155/2014/210469

Table 2.

Genes classified in inflammatory response and angiogenesis.

Biological process Gene name Gene ID Differ expre (fold)* Description
Inflammatory response
CCL20 NM_004591 −103.53 Chemokine (C-C motif) ligand 20
CCL5 NM_002985 −3.54 Chemokine (C-C motif) ligand 5
CCR5 NM_000579 −2.03 Chemokine (C-C motif) receptor 5
CXCL3 NM_002090 −10.03 Chemokine (C-X-C motif) ligand 3
CXCL2 M57731 −2.94 Chemokine (C-X-C motif) ligand 2
CXCL1 NM_001511 −3.01 Chemokine (C-X-C motif) ligand 1
CXCL9 NM_002416 −2.65 Chemokine (C-X-C motif) ligand 9
CXCL13 NM_006419 −2.62 Chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)
CXCR4 AF348491 −2.63 Chemokine (C-X-C motif) receptor 4
PTGS2 AY151286 −34.01 Prostaglandin-endoperoxide synthase 2
IL6 NM_000600 −32.07 Interleukin 6 (interferon, beta 2)
IL23A AF043179 −16.44 Enhancer of polycomb homolog 1 (Drosophila)
IL8 NM_000584 −8.17 Interleukin 8
IL1B NM_000576 −2.28 Interleukin 1, beta
IL1RN BE563442 −2.80 Interleukin 1 receptor antagonist
S100A8 NM_002964 −16.53 S100 calcium binding protein A8
S100A9 NM_002965 −2.79 S100 calcium binding protein A9
LBP M35533 −11.36 Lipopolysaccharide binding protein
APOE NM_000041 −9.23 Apolipoprotein E
FABP4 AI766029 −6.98 Fatty acid binding protein 4, adipocyte
LYZ U25677 −6.37 Lysozyme (renal amyloidosis)
ITIH4 AI004137 −6.33 Inter-alpha (globulin) inhibitor H4
BDKRB2 NM_000623 −6.01 Bradykinin receptor B2
TLR8 AW872374 −5.55 Toll-like receptor 8
TLR7 NM_016562 −3.34 Toll-like receptor 7
TLR5 AF051151 −3.00 Toll-like receptor 5
TLR4 NM_003266 −2.40 Toll-like receptor 4
TLR2 NM_003264 −2.20 Toll-like receptor 2
TLR1 AL050262 −2.66 Toll-like receptor 1
AOX1 AB046692 −5.34 Aldehyde oxidase 1
FCER1A BC005912 −5.19 Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
CFD NM_001928 −4.99 Complement factor D (adipsin)
CFI BC020718 −3.37 Complement factor I
CFB NM_001710 −2.39 Complement factor B
C3 NM_000064 −2.32 Complement component 3
CR1 AI052659 −2.24 Complement component (3b/4b) receptor 1 (Knops blood group)
C1RL NM_016546 −2.01 Complement component 1, r subcomponent-like
C1QA NM_015991 −2.20 Complement component 1, q subcomponent, A chain
C1QB NM_000491 −2.10 Complement component 1, q subcomponent, B chain
AOAH NM_001637 −4.89 Acyloxyacyl hydrolase (neutrophil)
AGT NM_000029 −4.66 Angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
BMP6 NM_001718 −4.48 Bone morphogenetic protein 6
PLA2G7 M80436 −3.95 Platelet-activating factor receptor
FOS BC004490 −3.95 V-fos FBJ murine osteosarcoma viral oncogene homolog
CD40 NM_001250 −3.68 CD40 molecule, TNF receptor superfamily member 5
CD163 NM_004244 −3.68 CD163 molecule
CD14 NM_000591 −3.25 CD14 molecule
MASP1 AI274095 −3.67 Mannan-binding lectin serine peptidase 1
F11R AF191495 −3.16 F11 receptor
ITGB2 L78790 −2.98 Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
NLRC4 NM_021209 −2.92 NLR family, CARD domain containing 4
AIF1 U19713 −2.76 Allograft inflammatory factor 1
ALOX5 NM_000698 −2.71 Arachidonate 5-lipoxygenase
NOD1 AF126484 −2.66 Nucleotide-binding oligomerization domain containing 1
JMJD3 AI830331 −2.46 Jumonji domain containing 3, histone lysine demethylase
SIGLEC1 NM_023068 −2.46 Sialic acid binding Ig-like lectin 1, sialoadhesin
TNFAIP6 AW188198 −2.37 Tumor necrosis factor, alpha-induced protein 6
LY86 NM_004271 −2.36 Lymphocyte antigen 86
AOC3 NM_003734 −2.31 Amine oxidase, copper containing 3 (vascular adhesion protein 1)
TNFRSF1B NM_001066 −2.21 Tumor necrosis factor receptor superfamily, member 1B
BCL6 S67779 −2.17 B-cell CLL/lymphoma 6 (zinc finger protein 51)
CLEC7A AF313468 −2.12 C-type lectin domain family 7, member A
CDO1 NM_001801 −2.11 Cysteine dioxygenase, type I
NFATC4 AI806528 −2.04 NF of activated T-cells, cytoplasmic, calcineurin-dependent 4
SERPINA3 NM_001085 5.20 Serpin peptidase inhibitor, clade A, member 3
SERPINA1 AF119873 3.58 Serpin peptidase inhibitor, clade A, member 1
C4BPA NM_000715 3.34 Complement component 4 binding protein, alpha
FN1 AJ276395 3.03 Fibronectin 1
B4GALT1 D29805 2.99 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1
GPR68 AI805006 2.40 G protein-coupled receptor 68
C7 NM_000587 2.36 Complement component 7
ANXA1 AU155094 2.23 Annexin A1
KLKB1 NM_000892 2.21 Cytochrome P450, family 4, subfamily V, polypeptide 2
Angiogenesis
PTGS2 AY151286 −34.00 Prostaglandin-endoperoxide synthase 2
BAI3 NM_001704 −33.48 Brain-specific angiogenesis inhibitor 3
IL6 NM_000600 −32.08 Interleukin 6 (interferon, beta 2)
IL8 NM_000584 −8.18 Interleukin 8
IL1B NM_000576 −2.28 Interleukin 1, beta
SFRP1 AF017987 −17.55 Secreted frizzled-related protein 1
ANGPTL4 AF169312 −11.43 Angiopoietin-like 4
ANGPT2 BE501356 −2.56 Angiopoietin 2
EREG NM_001432 −8.60 Epiregulin
VEGFA M27281 −7.91 Vascular endothelial growth factor A
VASH1 AU152507 −4.24 Vasohibin 1
FLT1 U01134 −3.62 Fms-related tyrosine kinase 1
PTPRB AL080103 −3.48 Protein tyrosine phosphatase, receptor type, B
FGF10 NM_004465 −3.34 Fibroblast growth factor 10
LIF NM_002309 −3.16 Leukemia inhibitory factor (cholinergic differentiation factor)
BTG1 BC009050 −3.11 B-cell translocation gene 1, anti-proliferative
DLL4 AB036931 −2.85 Delta-like 4 (Drosophila)
SOX17 NM_022454 −2.45 SRY (sex determining region Y)-box 17
EPAS1 NM_001430 −2.43 Endothelial PAS domain protein 1
CTNNB1 AB062292 −2.35 Catenin (cadherin-associated protein), beta 1, 88 kDa
TGFBR2 NM_003242 −2.35 Transforming growth factor, beta receptor II (70/80 kDa)
TYMP NM_001953 −2.34 Thymidine phosphorylase
C3 NM_000064 −2.32 Complement component 3
NRP1 AF280547 −2.19 Neuropilin 1
NOTCH4 AI743713 −2.17 Notch homolog 4 (Drosophila)
TSPAN12 AI056699 −2.16 Tetraspanin 12
ADAM8 NM_001109 −2.15 ADAM metallopeptidase domain 8
RHOB AI263909 −2.12 Ras homolog gene family, member B
HHEX NM_001529 −2.12 Hematopoietically expressed homeobox
THBS1 BF055462 −2.05 Thrombospondin 1
KDR NM_002253 −2.03 Kinase insert domain receptor (a type III receptor tyrosine kinase)
GREM1 NM_013372 15.86 Gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)
FGFR2 AB030078 4.49 Fibroblast growth factor receptor 2
FGF1 X59065 2.39 fibroblast growth factor 1 (acidic)
FGF18 AI798863 2.33 Fibroblast growth factor 18
COL8A2 AI806793 4.46 Collagen, type VIII, alpha 2
COL8A1 BE877796 3.30 Collagen, type VIII, alpha 1
ARHGAP22 NM_021226 4.45 Rho GTPase activating protein 22
TNFRSF12A NM_016639 3.23 Tumor necrosis factor receptor superfamily, member 12A
CSPG4 BE857703 3.14 Chondroitin sulfate proteoglycan 4
WNT5B NM_030775 3.10 Wingless-type MMTV integration site family, member 5B
FN1 AJ276395 3.03 Fibronectin 1
SFRP2 AF311912 3.00 Secreted frizzled-related protein 2
B4GALT1 D29805 2.99 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1
ANGPT1 NM_001146 2.62 Angiopoietin 1
MFGE8 BC003610 2.39 Milk fat globule-EGF factor 8 protein
TGFB2 NM_003238 2.36 Transforming growth factor, beta 2
CYR61 NM_001554 2.30 Cysteine-rich, angiogenic inducer, 61
MEOX2 NM_005924 2.15 Mesenchyme homeobox 2
PLXDC1 NM_020405 2.09 Plexin domain containing 1
TBXA2R NM_001060 2.09 Thromboxane A2 receptor

*Negative number indicates decreased expression and positive number indicates increased expression (fold change).