Table 2.
Genes classified in inflammatory response and angiogenesis.
Biological process | Gene name | Gene ID | Differ expre (fold)* | Description |
---|---|---|---|---|
Inflammatory response | ||||
CCL20 | NM_004591 | −103.53 | Chemokine (C-C motif) ligand 20 | |
CCL5 | NM_002985 | −3.54 | Chemokine (C-C motif) ligand 5 | |
CCR5 | NM_000579 | −2.03 | Chemokine (C-C motif) receptor 5 | |
CXCL3 | NM_002090 | −10.03 | Chemokine (C-X-C motif) ligand 3 | |
CXCL2 | M57731 | −2.94 | Chemokine (C-X-C motif) ligand 2 | |
CXCL1 | NM_001511 | −3.01 | Chemokine (C-X-C motif) ligand 1 | |
CXCL9 | NM_002416 | −2.65 | Chemokine (C-X-C motif) ligand 9 | |
CXCL13 | NM_006419 | −2.62 | Chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant) | |
CXCR4 | AF348491 | −2.63 | Chemokine (C-X-C motif) receptor 4 | |
PTGS2 | AY151286 | −34.01 | Prostaglandin-endoperoxide synthase 2 | |
IL6 | NM_000600 | −32.07 | Interleukin 6 (interferon, beta 2) | |
IL23A | AF043179 | −16.44 | Enhancer of polycomb homolog 1 (Drosophila) | |
IL8 | NM_000584 | −8.17 | Interleukin 8 | |
IL1B | NM_000576 | −2.28 | Interleukin 1, beta | |
IL1RN | BE563442 | −2.80 | Interleukin 1 receptor antagonist | |
S100A8 | NM_002964 | −16.53 | S100 calcium binding protein A8 | |
S100A9 | NM_002965 | −2.79 | S100 calcium binding protein A9 | |
LBP | M35533 | −11.36 | Lipopolysaccharide binding protein | |
APOE | NM_000041 | −9.23 | Apolipoprotein E | |
FABP4 | AI766029 | −6.98 | Fatty acid binding protein 4, adipocyte | |
LYZ | U25677 | −6.37 | Lysozyme (renal amyloidosis) | |
ITIH4 | AI004137 | −6.33 | Inter-alpha (globulin) inhibitor H4 | |
BDKRB2 | NM_000623 | −6.01 | Bradykinin receptor B2 | |
TLR8 | AW872374 | −5.55 | Toll-like receptor 8 | |
TLR7 | NM_016562 | −3.34 | Toll-like receptor 7 | |
TLR5 | AF051151 | −3.00 | Toll-like receptor 5 | |
TLR4 | NM_003266 | −2.40 | Toll-like receptor 4 | |
TLR2 | NM_003264 | −2.20 | Toll-like receptor 2 | |
TLR1 | AL050262 | −2.66 | Toll-like receptor 1 | |
AOX1 | AB046692 | −5.34 | Aldehyde oxidase 1 | |
FCER1A | BC005912 | −5.19 | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | |
CFD | NM_001928 | −4.99 | Complement factor D (adipsin) | |
CFI | BC020718 | −3.37 | Complement factor I | |
CFB | NM_001710 | −2.39 | Complement factor B | |
C3 | NM_000064 | −2.32 | Complement component 3 | |
CR1 | AI052659 | −2.24 | Complement component (3b/4b) receptor 1 (Knops blood group) | |
C1RL | NM_016546 | −2.01 | Complement component 1, r subcomponent-like | |
C1QA | NM_015991 | −2.20 | Complement component 1, q subcomponent, A chain | |
C1QB | NM_000491 | −2.10 | Complement component 1, q subcomponent, B chain | |
AOAH | NM_001637 | −4.89 | Acyloxyacyl hydrolase (neutrophil) | |
AGT | NM_000029 | −4.66 | Angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | |
BMP6 | NM_001718 | −4.48 | Bone morphogenetic protein 6 | |
PLA2G7 | M80436 | −3.95 | Platelet-activating factor receptor | |
FOS | BC004490 | −3.95 | V-fos FBJ murine osteosarcoma viral oncogene homolog | |
CD40 | NM_001250 | −3.68 | CD40 molecule, TNF receptor superfamily member 5 | |
CD163 | NM_004244 | −3.68 | CD163 molecule | |
CD14 | NM_000591 | −3.25 | CD14 molecule | |
MASP1 | AI274095 | −3.67 | Mannan-binding lectin serine peptidase 1 | |
F11R | AF191495 | −3.16 | F11 receptor | |
ITGB2 | L78790 | −2.98 | Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | |
NLRC4 | NM_021209 | −2.92 | NLR family, CARD domain containing 4 | |
AIF1 | U19713 | −2.76 | Allograft inflammatory factor 1 | |
ALOX5 | NM_000698 | −2.71 | Arachidonate 5-lipoxygenase | |
NOD1 | AF126484 | −2.66 | Nucleotide-binding oligomerization domain containing 1 | |
JMJD3 | AI830331 | −2.46 | Jumonji domain containing 3, histone lysine demethylase | |
SIGLEC1 | NM_023068 | −2.46 | Sialic acid binding Ig-like lectin 1, sialoadhesin | |
TNFAIP6 | AW188198 | −2.37 | Tumor necrosis factor, alpha-induced protein 6 | |
LY86 | NM_004271 | −2.36 | Lymphocyte antigen 86 | |
AOC3 | NM_003734 | −2.31 | Amine oxidase, copper containing 3 (vascular adhesion protein 1) | |
TNFRSF1B | NM_001066 | −2.21 | Tumor necrosis factor receptor superfamily, member 1B | |
BCL6 | S67779 | −2.17 | B-cell CLL/lymphoma 6 (zinc finger protein 51) | |
CLEC7A | AF313468 | −2.12 | C-type lectin domain family 7, member A | |
CDO1 | NM_001801 | −2.11 | Cysteine dioxygenase, type I | |
NFATC4 | AI806528 | −2.04 | NF of activated T-cells, cytoplasmic, calcineurin-dependent 4 | |
SERPINA3 | NM_001085 | 5.20 | Serpin peptidase inhibitor, clade A, member 3 | |
SERPINA1 | AF119873 | 3.58 | Serpin peptidase inhibitor, clade A, member 1 | |
C4BPA | NM_000715 | 3.34 | Complement component 4 binding protein, alpha | |
FN1 | AJ276395 | 3.03 | Fibronectin 1 | |
B4GALT1 | D29805 | 2.99 | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1 | |
GPR68 | AI805006 | 2.40 | G protein-coupled receptor 68 | |
C7 | NM_000587 | 2.36 | Complement component 7 | |
ANXA1 | AU155094 | 2.23 | Annexin A1 | |
KLKB1 | NM_000892 | 2.21 | Cytochrome P450, family 4, subfamily V, polypeptide 2 | |
Angiogenesis | ||||
PTGS2 | AY151286 | −34.00 | Prostaglandin-endoperoxide synthase 2 | |
BAI3 | NM_001704 | −33.48 | Brain-specific angiogenesis inhibitor 3 | |
IL6 | NM_000600 | −32.08 | Interleukin 6 (interferon, beta 2) | |
IL8 | NM_000584 | −8.18 | Interleukin 8 | |
IL1B | NM_000576 | −2.28 | Interleukin 1, beta | |
SFRP1 | AF017987 | −17.55 | Secreted frizzled-related protein 1 | |
ANGPTL4 | AF169312 | −11.43 | Angiopoietin-like 4 | |
ANGPT2 | BE501356 | −2.56 | Angiopoietin 2 | |
EREG | NM_001432 | −8.60 | Epiregulin | |
VEGFA | M27281 | −7.91 | Vascular endothelial growth factor A | |
VASH1 | AU152507 | −4.24 | Vasohibin 1 | |
FLT1 | U01134 | −3.62 | Fms-related tyrosine kinase 1 | |
PTPRB | AL080103 | −3.48 | Protein tyrosine phosphatase, receptor type, B | |
FGF10 | NM_004465 | −3.34 | Fibroblast growth factor 10 | |
LIF | NM_002309 | −3.16 | Leukemia inhibitory factor (cholinergic differentiation factor) | |
BTG1 | BC009050 | −3.11 | B-cell translocation gene 1, anti-proliferative | |
DLL4 | AB036931 | −2.85 | Delta-like 4 (Drosophila) | |
SOX17 | NM_022454 | −2.45 | SRY (sex determining region Y)-box 17 | |
EPAS1 | NM_001430 | −2.43 | Endothelial PAS domain protein 1 | |
CTNNB1 | AB062292 | −2.35 | Catenin (cadherin-associated protein), beta 1, 88 kDa | |
TGFBR2 | NM_003242 | −2.35 | Transforming growth factor, beta receptor II (70/80 kDa) | |
TYMP | NM_001953 | −2.34 | Thymidine phosphorylase | |
C3 | NM_000064 | −2.32 | Complement component 3 | |
NRP1 | AF280547 | −2.19 | Neuropilin 1 | |
NOTCH4 | AI743713 | −2.17 | Notch homolog 4 (Drosophila) | |
TSPAN12 | AI056699 | −2.16 | Tetraspanin 12 | |
ADAM8 | NM_001109 | −2.15 | ADAM metallopeptidase domain 8 | |
RHOB | AI263909 | −2.12 | Ras homolog gene family, member B | |
HHEX | NM_001529 | −2.12 | Hematopoietically expressed homeobox | |
THBS1 | BF055462 | −2.05 | Thrombospondin 1 | |
KDR | NM_002253 | −2.03 | Kinase insert domain receptor (a type III receptor tyrosine kinase) | |
GREM1 | NM_013372 | 15.86 | Gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) | |
FGFR2 | AB030078 | 4.49 | Fibroblast growth factor receptor 2 | |
FGF1 | X59065 | 2.39 | fibroblast growth factor 1 (acidic) | |
FGF18 | AI798863 | 2.33 | Fibroblast growth factor 18 | |
COL8A2 | AI806793 | 4.46 | Collagen, type VIII, alpha 2 | |
COL8A1 | BE877796 | 3.30 | Collagen, type VIII, alpha 1 | |
ARHGAP22 | NM_021226 | 4.45 | Rho GTPase activating protein 22 | |
TNFRSF12A | NM_016639 | 3.23 | Tumor necrosis factor receptor superfamily, member 12A | |
CSPG4 | BE857703 | 3.14 | Chondroitin sulfate proteoglycan 4 | |
WNT5B | NM_030775 | 3.10 | Wingless-type MMTV integration site family, member 5B | |
FN1 | AJ276395 | 3.03 | Fibronectin 1 | |
SFRP2 | AF311912 | 3.00 | Secreted frizzled-related protein 2 | |
B4GALT1 | D29805 | 2.99 | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1 | |
ANGPT1 | NM_001146 | 2.62 | Angiopoietin 1 | |
MFGE8 | BC003610 | 2.39 | Milk fat globule-EGF factor 8 protein | |
TGFB2 | NM_003238 | 2.36 | Transforming growth factor, beta 2 | |
CYR61 | NM_001554 | 2.30 | Cysteine-rich, angiogenic inducer, 61 | |
MEOX2 | NM_005924 | 2.15 | Mesenchyme homeobox 2 | |
PLXDC1 | NM_020405 | 2.09 | Plexin domain containing 1 | |
TBXA2R | NM_001060 | 2.09 | Thromboxane A2 receptor |
*Negative number indicates decreased expression and positive number indicates increased expression (fold change).