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. 2014 Dec 3;14:660. doi: 10.1186/s12879-014-0660-7

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© Tanner et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Serum IDO activity is negatively correlated with the 85A peptide specific IFN-γ ELISPOT response. IDO activity at baseline for both UK and South African volunteers was correlated with the 85A peptide specific IFN-γ ELISPOT response at A) week 4 and B) week 24 following vaccination with MVA85A (Spearman’s correlation P < .05).