. 2014 Dec 2;14:901. doi: 10.1186/1471-2407-14-901

Table 3.

Clinico-pathological parameters of high grade, invasive bladder tumors in relation to ST6GAL1 protein expression

		ST6GAL1 IRS ^b
		n ^a	low ^{(IRS 0–3)}	high ^{(IRS 4–12)}	P-value ^c	Spearmanrs
*Parameter:*
Age at diagnosis
	≤69 years	27	10	17	0.987	0.002
	>69 years	38	14	24	0.987	0.002
Gender
	Female	21	8	13	0.894	0.017
	Male	44	16	28	0.894	0.017
Histological tumor grade^d
	G2	7	4	3	0.247	0.146
	G3	58	20	38	0.247	0.146
Tumor stage^e
	pT1-pT2	29	7	22	0.056	-0.238
	pT3-pT4	36	22	19	0.056	-0.238
Lymph node status
	Negative	39	11	28	0.017	-0.321
	Positive	16	10	6

^aOnly patients with primary bladder cancer were included; ^bcut-off: median immunoreactive score (IRS) according to Remmele and Stegner [23]; ^cFisher’s exact test; ^daccording to WHO 1973 classification according to WHO 2004 classification; ^eaccording to WHO 2004 classification; significant p-values are marked in bold face.