Table 4.
Predictors of 5-year survival on univariate analysis
| Event (n (%)) | Hazard ratio | 95% CI | Pvalue | |
|---|---|---|---|---|
| Diagnosis age group | <0.0001 | |||
| 45-79 | 661 (45.31) | 1.54 | 1.02-2.34 | |
| 80+ | 371 (66.61) | 2.87 | 1.89-4.38 | |
| <45 | 23 (32.86) | 1 | Ref | |
| Gender | 0.4521 | |||
| Female | 478 (49.64) | 1 | Ref | |
| Male | 577 (51.38) | 1.05 | 0.93-1.18 | |
| Site | 0.0069 | |||
| Colon | 719 (52.25) | 1 | Ref | |
| Rectosigmoid | 103 (50.99) | 0.93 | 0.75-1.14 | |
| Rectum | 233 (45.87) | 0.79 | 0.68-0.91 | |
| Collaborative stage | <0.0001 | |||
| I | 116 (28.78) | 1 | Ref | |
| II | 194 (33.74) | 1.21 | 0.96-1.53 | |
| III | 284 (46.56) | 1.87 | 1.50-2.32 | |
| IV | 413 (94.08) | 8.46 | 6.85-10.44 | |
| Unknown/NA | 48 (81.36) | 6.7 | 4.78-9.39 | |
| Income quintile | <0.0001 | |||
| 1 | 276 (59.74) | 1 | Ref | |
| 2 | 244 (53.74) | 0.88 | 0.74-1.05 | |
| 3 | 209 (47.83) | 0.73 | 0.61-0.88 | |
| 4 | 165 (44.12) | 0.66 | 0.54-0.80 | |
| 5 | 139 (41.49) | 0.61 | 0.50-0.75 | |
| NF | 22 (91.67) | 2.75 | 1.78-4.24 | |
| Grade/differentiated | <0.0001 | |||
| 1 - well differentiated | 43 (34.68) | 1 | Ref | |
| 2 - moderately differentiated | 624 (45.32) | 1.39 | 1.02-1.89 | |
| 3 - poorly differentiated | 152 (57.79) | 2.18 | 1.56-3.06 | |
| 4 - undifferentiated | 5 (62.50) | 3 | 1.19-7.57 | |
| 9 - not determined/not available | 231 (73.57) | 3.65 | 2.64-5.06 | |
| Comorbidity | <0.0001 | |||
| CCI count <1 | 239 (28.55) | 1 | Ref | |
| CCI count =1 | 454 (59.35) | 2.74 | 2.34-3.20 | |
| CCI count >1 | 362 (74.79) | 4.28 | 3.63-5.04 | |
| Residence | 0.4599 | |||
| Rural | 404 (51.86) | 1 | Ref | |
| Urban | 651 (49.81) | 0.95 | 0.84-1.08 | |
| Distance from CancerCare | 0.348 | |||
| <21 km | 599 (49.10) | 1 | Ref | |
| 21-100 km | 170 (50.60) | 1.02 | 0.86-1.20 | |
| 101-500 km | 257 (53.99) | 1.12 | 0.97-1.29 | |
| 501+ km | 29 (53.70) | 1.25 | 0.86-1.81 | |
| Surgery type | <0.0001 | |||
| Major surgery | 707 (43.43) | 0.17 | 0.15-0.19 | |
| Local resection | 15 (25.86) | 0.09 | 0.05-0.15 | |
| Polypectomy | 27 (38.57) | 0.14 | 0.10-0.21 | |
| None | 306 (92.73) | 1 | Ref | |
| Chemotherapy type | <0.0001 | |||
| None | 690 (51.49) | 1 | Ref | |
| Neoadjuvant | 19 (35.85) | 0.54 | 0.34-0.85 | |
| Adjuvant | 254 (43.94) | 0.71 | 0.62-0.82 | |
| Palliative | 83 (90.22) | 2.53 | 2.01-3.18 | |
| Adjuvant with local procedure | 9 (39.13) | 0.61 | 0.32-1.18 | |
| Radiation therapy type | <0.0001 | |||
| None | 929 (52.02) | 1 | Ref | |
| Neoadjuvant | 18 (29.51) | 0.45 | 0.28-0.71 | |
| Adjuvant | 65 (35.91) | 0.56 | 0.43-0.71 | |
| Palliative | 39 (92.86) | 2.67 | 1.94-3.69 | |
| Adjuvant with local procedure | 4 (25.00) | 0.38 | 0.14-1.00 |
CCI (Charlson Comorbidity Index); NA (Not Available); NF (Not Formatted).