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. 2014 Dec 7;15(1):156. doi: 10.1186/s12931-014-0156-4

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© Qi et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Decrease of body weight in the COPD model rats. The body weight of the COPD model rats (filled circles in pink) (n = 13) was significantly reduced, in comparison to the body weight in the control rats (filled circles in black) (n = 12). AICAR treatment (n = 13, filled circles in red) prevented the reduction of body weight in the COPD model rats. **p < 0.01; student t test.