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Pathological changes of the lungs in control rats and COPD model rats that were treated with vehicles, AICAR and/or resveratrol at week 20 (H & E stained). (A) Control rats; (B) COPD rats with vehicle; (C) COPD rats with AICAR treatment; and (D) COPD rats with resveratrol treatment. Amplification ×200. Scale bar, 20 μm.
