Table 2.
Proteins upregulated twofold or more by 15 mM furfural ( P ≤0.05)
| Locus | Fold change | Description | P -value |
|---|---|---|---|
| Amino acid biosynthesis | |||
| Teth39_0141 | 2.22 | Threonine synthase | 0.015 |
| Teth39_0223 | 4.31 | N-acetyl-gamma-glutamyl-phosphate reductase | 0.001 |
| Teth39_0224 | 6.61 | Arginine biosynthesis bifunctional protein ArgJ | 0.000 |
| Teth39_0225 | 2.50 | Acetylglutamate kinase | 0.010 |
| Teth39_0226 | 2.65 | Acetylornithine and succinylornithine aminotransferase | 0.038 |
| Teth39_0227 | 7.69 | Carbamoyl phosphate synthase, small subunit | 0.010 |
| Teth39_0228 | 12.73 | Carbamoyl phosphate synthase, large subunit | 0.008 |
| Teth39_0229 | 5.74 | Argininosuccinate synthase | 0.000 |
| Teth39_0279 | 3.50 | Cysteine synthase A | 0.001 |
| Teth39_0280 | 6.68 | Cysteine desulfurase | 0.001 |
| Teth39_0281 | 9.01 | tRNA methyltransferase | 0.014 |
| Teth39_0559 | 2.56 | Diaminopimelate decarboxylase | 0.001 |
| Teth39_0983 | 3.14 | Prephenate dehydratase | 0.002 |
| Teth39_1666 | 2.17 | Glutamine synthetase, catalytic region | 0.003 |
| Teth39_1810 | 3.56 | Aspartate 1-decarboxylase | 0.033 |
| Carbohydrate metabolism | |||
| Teth39_0611 | 2.28 | Beta-galactosidase | 0.011 |
| Teth39_0744 | 2.26 | Mannose-6-phosphate isomerase, class I | 0.034 |
| Teth39_1512 | 3.34 | Kojibiose phosphorylase | 0.043 |
| Cell division/sporulation/motility | |||
| Teth39_1000 | 2.05 | SpoIID/LytB domain | 0.009 |
| Teth39_1257 | 4.17 | Flagellar M-ring protein FliF | 0.043 |
| Teth39_1280 | 2.08 | Chromosome segregation protein SMC | 0.008 |
| Chaperones | |||
| Teth39_0115 | 2.15 | Chaperonin Cpn10 | 0.013 |
| Teth39_1392 | 2.21 | Chaperone protein DnaJ | 0.005 |
| Energy related | |||
| Teth39_1820 | 2.04 | Homocitrate synthase | 0.003 |
| Teth39_2064 | 6.75 | 2-hydroxyacid dehydrogenase, NAD-binding | 0.019 |
| Hypothetical proteins | |||
| Teth39_0463 | 2.28 | Hypothetical protein | 0.012 |
| Teth39_0919 | 2.78 | Hypothetical protein | 0.023 |
| Iron-sulfur cluster metabolism | |||
| Teth39_0116 | 2.14 | FeS assembly ATPase SufC | 0.020 |
| Teth39_0117 | 2.65 | FeS assembly protein SufB | 0.001 |
| Teth39_0118 | 2.97 | SufBD protein | 0.000 |
| Teth39_0120 | 2.66 | SUF system FeS assembly protein, NifU family | 0.001 |
| Nucleotide related | |||
| Teth39_0775 | 2.04 | MutS2 family protein | 0.005 |
| Teth39_1049 | 2.07 | tRNA methyltransferase | 0.018 |
| Teth39_1323 | 2.46 | DNA-directed RNA polymerase, omega subunit | 0.005 |
| Teth39_1713 | 2.12 | Phosphoribosylformylglycinamidine synthase II | 0.006 |
| Teth39_1803 | 36.39 | Phosphoribosylaminoimidazole carboxylase, ATPase subunit | 0.000 |
| Teth39_1828 | 2.76 | Cytidine deaminase | 0.009 |
| Teth39_1832 | 2.14 | ABC transporter related | 0.004 |
| Redox proteins | |||
| Teth39_0646 | 3.61 | FAD-dependent pyridine nucleotide disulfide oxidoreductase | 0.005 |
| Teth39_0720 | 3.77 | 4Fe-4S ferredoxin, iron-sulfur binding domain protein | 0.044 |
| Teth39_1597 | 6.84 | Iron-containing alcohol dehydrogenase | 0.000 |
| Teth39_1598 | 6.32 | Aldo/keto reductase | 0.000 |
| Ribosomal proteins | |||
| Teth39_0365 | 2.00 | Ribosomal protein L7/L12 | 0.020 |
| Teth39_1753 | 2.01 | RNA binding S1 domain protein | 0.001 |
| Teth39_2275 | 2.33 | Ribosomal protein S6 | 0.006 |
| Transporters | |||
| Teth39_0231 | 2.85 | Calcium translocating P-type ATPase, PMCA-type | 0.001 |
| Teth39_0278 | 2.82 | Heavy metal translocating P-type ATPase | 0.036 |
| Teth39_0282 | 4.65 | Copper translocating P-type ATPase | 0.004 |
| Teth39_1033 | 2.26 | Efflux transporter, RND family, MFP subunit | 0.015 |
| Teth39_1765 | 4.62 | Extracellular solute-binding protein, family 3 | 0.001 |
| Teth39_2232 | 2.43 | Type IV secretory pathway VirB4 components-like protein | 0.011 |
| Vitamin related | |||
| Teth39_0307 | 3.10 | Biotin/lipoyl attachment domain-containing protein | 0.007 |
| Teth39_1205 | 2.03 | Riboflavin biosynthesis protein RibF | 0.001 |
| Teth39_1559 | 2.00 | SNO glutamine amidotransferase | 0.001 |
Sorted by general cellular function. Proteins in boldface are regulated greater than fivefold. Descriptions are from the National Center for Biotechnology Information.