Table 3.
Proteins downregulated twofold or more by 15 mM furfural ( P ≤0.05)
| Locus | Fold change | Description | P -value |
|---|---|---|---|
| Amino acid metabolism | |||
| Teth39_0216 | -3.10 | Glutamate synthase, homotetrameric | 0.000 |
| Teth39_0217 | -2.47 | Oxidoreductase FAD/NAD(P)-binding domain | 0.004 |
| Teth39_0487 | -2.15 | Alanine racemase | 0.038 |
| Teth39_1661 | -3.77 | Glutamine amidotransferase, class II | 0.016 |
| Teth39_2007 | -2.58 | Aromatic amino acid beta-eliminating lyase | 0.004 |
| Cell division/sporulation/motility | |||
| Teth39_0175 | -52.70 | Peptidoglycan-binding LysM | 0.000 |
| Teth39_0252 | -30.04 | YabP family protein | 0.000 |
| Teth39_1446 | -2.42 | Cell division topological specificity factor MinE | 0.016 |
| Teth39_1772 | -2.33 | Flagellar protein FlaG protein | 0.011 |
| Teth39_1783 | -2.51 | Flagellar hook-associated protein 3 | 0.009 |
| Energy related | |||
| Teth39_0466 | -2.27 | Thiamine pyrophosphate enzyme domain | 0.038 |
| Hydrogenase related | |||
| Teth39_0221 | -2.17 | Hydrogenase with PAS/PAC sensor | 0.005 |
| Teth39_1458 | -2.05 | Hypothetical protein | 0.005 |
| Teth39_1459 | -24.50 | Histidine kinase | 0.000 |
| Hypothetical proteins | |||
| Teth39_0794 | -5.93 | Hypothetical protein | 0.041 |
| Teth39_0842 | -36.68 | Hypothetical protein | 0.000 |
| Nucleotide related | |||
| Teth39_1357 | -2.51 | Metal-dependent phosphohydrolase | 0.002 |
| Teth39_2157 | -9.29 | SirA family protein | 0.000 |
| Redox proteins | |||
| Teth39_0445 | -2.19 | Thioredoxin reductase | 0.002 |
| Teth39_1916 | -2.73 | Oxidoreductase FAD/NAD(P)-binding domain | 0.001 |
| Teth39_1917 | -4.88 | 4Fe-4S ferredoxin, iron-sulfur binding domain | 0.000 |
| Teth39_2155 | -4.30 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | 0.000 |
| Transcriptional regulator | |||
| Teth39_0150 | -2.56 | Transcriptional regulator, DeoR family | 0.011 |
| Teth39_0757 | -3.07 | Putative cold-shock DNA-binding domain protein | 0.029 |
| Teth39_1109 | -2.27 | Sporulation transcriptional activator Spo0A | 0.006 |
| Teth39_1292 | -2.06 | Hypothetical protein | 0.019 |
| Teth39_1796 | -2.17 | Two-component transcriptional regulator, winged helix family | 0.015 |
| Transporters | |||
| Teth39_0333 | -2.98 | PTS system, fructose subfamily, IIC subunit | 0.001 |
| Teth39_0334 | -2.90 | PTS system, fructose-specific, IIB subunit | 0.019 |
| Vitamin related | |||
| Teth39_0787 | -4.71 | Lipoic acid synthetase | 0.033 |
| Other | |||
| Teth39_0542 | -2.43 | Dihydroxyacetone kinase, DhaK subunit | 0.006 |
| Teth39_1065 | -2.21 | HAD superfamily (subfamily IIIA) phosphatase, TIGR01668 | 0.024 |
| Teth39_1216 | -2.04 | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase | 0.011 |
Sorted by general cellular function. Proteins in boldface are regulated greater than fivefold. Descriptions are from the National Center for Biotechnology Information.