Table 5.
Amino acid substitution of the CR8033 epitope
| CR8033 (Head) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 154 | 155 | 157 | 165 | 175 | 177 | 178 | 215 | 218 | 219 | 255 | 256 | 258 | |
| Yamagata 88 | T | S | S | N | V | R | - | Q | N | L | L | P | S |
| DSO 010147 2007 | . | . | . | I | . | K | . | . | . | . | . | . | . |
| Vacc0405N 05S B Jilin 20 2003 | . | . | . | S | . | K | . | P | . | . | . | . | . |
| Vacc0506N B Jiangsu 10 2003 | . | . | . | S | . | K | . | . | . | . | . | . | . |
| Vacc0809NS B Florida 4 2006 | . | . | . | S | . | K | . | . | . | . | . | . | . |
| Vacc1213N B Wisconsin 01 2010 | . | . | . | I | . | K | . | . | S | . | . | . | . |
| Singapore 2010–2011 (Yam) | . | . | . | I | . | K | . | . | . | . | . | . | . |
| B Singapore 04 1991 | . | . | . | D | . | . | . | . | . | . | . | . | . |
| B Singapore 11 1994 | . | . | . | S | . | . | . | . | . | . | . | . | . |
| B Singapore 22 1998 | . | . | . | S | . | . | . | . | . | . | . | . | . |
| B Singapore 31 1998 | . | . | . | S | . | . | . | . | . | . | . | . | . |
| B Singapore 35 1998 | . | . | . | S | . | . | . | . | . | . | . | . | . |
| B Singapore 222 1979 | . | . | . | N | . | K | . | . | K | . | . | . | . |
| B Singapore 1964 | . | . | . | K | . | K | . | . | T | . | . | Q | . |
| Victoria 87 | T | S | S | N | V | K | N | Q | K | L | L | P | S |
| DSO Victoria | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Vacc04S B Hong Kong 330 2001 | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Vacc0608NS B Malaysia 2506 2004 | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Vacc0912NS B Brisbane 60 2008 | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Singapore 2010–2011 (Vic) | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Lee40 | T | S | S | N | I | K | - | Q | R | L | L | K | S |
Specimens listed under B Yamagata 16 88 belong to the Yamagata lineage while specimens listed under B Victoria 2 87 belong to the Victoria lineage. DSO Victoria: specimens sequenced in this study belonging to the Victoria lineage. Identical amino acids are marked by a dot (.) and X refers to an unknown amino acid.