Table 6.
Amino acid substitution of the CR8071 epitope
| CR8071 (Head) | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 52 | 53 | 55 | 56 | 67 | 73 | 74 | 75 | 76 | 77 | 100 | 101 | 105 | 300 | 301 | 302 | 303 | 305 | |
| Yamagata 88 | T | K | H | F | K | L | N | C | C | T | H | E | V | G | S | L | P | I |
| DSO 010147 2007 | . | . | Y | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Vacc0405N 05S B Jilin 20 2003 | . | . | Y | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Vacc0506N B Jiangsu 10 2003 | . | . | Y | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Vacc0809NS B Florida 4 2006 | . | . | Y | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Vacc1213N B Wisconsin 01 2010 | . | . | Y | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Singapore 2010-2011 | . | . | Y | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 04 1991 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 11 1994 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 22 1998 | . | . | Y | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 31 1998 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 35 1998 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 222 1979 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 1964 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Victoria 87 | T | K | H | F | K | L | N | C | C | T | H | E | V | G | S | L | P | I |
| DSO Victoria | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| DSO Victoria 2009 | I | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | |
| DSO 010151 2005 | . | R | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| DSO 090114 2004 | . | . | . | . | . | F | . | . | . | . | . | . | . | . | . | . | . | . |
| Vacc04S B Hong Kong 330 2001 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Vacc0608NS B Malaysia 2506 2004 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Vacc0912NS B Brisbane 60 2008 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 1H 2010 | . | . | . | . | . | P | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 17H 2010 | . | . | . | . | . | P | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 32C 2010 | . | . | . | . | . | P | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 57H 2010 | . | . | . | . | . | P | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 65H 2010 | . | . | . | . | . | P | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 71H 2010 | . | . | . | . | . | P | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 77C 2011 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| B Singapore 90C 2011 | . | . | . | . | . | P | . | . | . | . | . | . | . | . | . | . | . | . |
| Lee40 | T | K | H | F | K | F | N | C | C | T | H | E | A | G | S | L | P | I |
Specimens listed under B Yamagata 16 88 belong to the Yamagata lineage while specimens listed under B Victoria 2 87 belong to the Victoria lineage. DSO Victoria: specimens sequenced in this study belonging to the Victoria lineage. Identical amino acids are marked by a dot (.) amino acid.