Table 7.

Amino acid substitution of the CR9117 epitope

	CR9117 (Stalk)
	43	45	46	47	321	322	323	380	381	382	383	398	400	403	404	407	408	410	411	414	418
Yamagata 88	G	I	P	L	S	K	P	I	A	G	W	A	L	T	Q	I	N	I	T	L	S
DSO 010147 2007	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Vacc0405N 05S B Jilin 20 2003	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Vacc0506N B Jiangsu 10 2003	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Vacc0809NS B Florida 4 2006	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Vacc1213N B Wisconsin 01 2010	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Singapore 2010-2011	.	.	.	.	.	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
B Singapore 04 1991	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
B Singapore 11 1994	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
B Singapore 22 1998	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
B Singapore 31 1998	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
B Singapore 35 1998	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
B Singapore 222 1979	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
B Singapore 1964	.	.	.	.	.	.	.	.	.	.	.	.	X	X	X	X	X	X	X	X	X
Victoria 87	G	I	P	L	S	K	P	I	A	G	W	A	L	T	Q	I	N	I	T	L	S
DSO Victoria	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
DSO 050629 2005	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
DSO 050599 2005	.	.	.	.	.	.	.	V	.	.	.	.	.	.	.	.	.	.	.	.	.
Vacc04S B Hong Kong 330 2001	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Vacc0608NS B Malaysia 2506 2004	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Vacc0912NS B Brisbane 60 2008	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Singapore 2010-2011	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Lee40	G	I	P	L	S	K	P	I	A	G	W	A	L	T	Q	I	N	I	T	L	S

Specimens listed under B Yamagata 16 88 belong to the Yamagata lineage while specimens listed under B Victoria 2 87 belong to the Victoria lineage. DSO Victoria: specimens sequenced in this study belonging to the Victoria lineage. Identical amino acids are marked by a dot (.) and X information unavailable.