Table 1.
Statistical significance of biochemical differences between the eye tissues.
| Metabolite | Homogeneity | Normality | Type of analysis | Cornea-CB*** | Cornea-iris*** | Cornea-lens*** | Cornea-retina*** | CB-retina*** | Iris-retina*** | Lens-retina*** |
|---|---|---|---|---|---|---|---|---|---|---|
| Ac | −* | +** | AW | − | − | − | − | − | − | − |
| Ala | +* | −** | KW | + | + | + | + | − | − | − |
| Arg | − | + | AW | − | − | − | − | − | − | − |
| Asc | + | + | A | + | + | − | + | − | − | + |
| ATP | − | + | AW | + | + | + | + | − | − | − |
| But | + | + | A | n/a | n/a | n/a | n/a | − | − | n/a |
| Ch | − | + | AW | − | − | n/a | + | − | − | n/a |
| Cr | + | − | KW | + | + | + | + | − | − | − |
| For | − | + | AW | + | + | + | + | − | − | − |
| GPC | + | + | A | + | + | + | n/a | n/a | n/a | n/a |
| Gln | − | + | AW | + | − | − | + | + | − | − |
| Glc | − | + | AW | n/a | n/a | + | n/a | n/a | n/a | n/a |
| Glu | − | + | AW | n/a | n/a | + | + | n/a | n/a | − |
| GMP | − | + | AW | n/a | n/a | n/a | n/a | − | + | n/a |
| GSH | − | − | − | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
| His | + | + | A | − | n/a | − | n/a | n/a | n/a | n/a |
| h-Tau | + | + | A | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
| Ile | + | − | KW | + | − | + | + | − | − | + |
| Lac | − | + | AW | + | + | − | + | − | − | + |
| Leu | − | + | AW | + | + | − | − | − | − | − |
| Met | + | + | A | n/a | n/a | n/a | − | n/a | n/a | n/a |
| m-In | − | + | AW | + | + | + | + | + | + | − |
| P-Ch | − | + | AW | n/a | n/a | n/a | n/a | − | − | − |
| P-Cr | + | + | A | n/a | n/a | n/a | n/a | − | − | + |
| Phe | + | + | A | − | − | − | − | − | − | − |
| Su | + | − | KW | + | n/a | + | − | + | n/a | − |
| Tau | − | + | AW | − | − | − | + | + | − | + |
| Tyr | − | + | AW | − | − | + | − | − | − | − |
| Val | + | + | A | − | − | − | − | − | − | − |
*homogeneity of the groups (+/−, yes/no); **normality of the distribution within the groups (+/−, yes/no); ***statistical significance of differences between the groups of samples (+/−, positive/negative); A: one-way analysis of variance (ANOVA); AW: ANOVA with method of Welch for treating unequal variances; K: the Kruskal-Wallis test; n/a: not applicable due to the lack of data for one or both groups of samples; CB: ciliary body. For metabolite labels see legend for Figure 1.