Table 3.

Spontaneous and stimulated cytokine production by peripheral blood cells in healthy donors and all patients with cirrhosis

	Healthy donors (n = 5)	All patients with cirrhosis (n = 19)	P value
Spontaneous TNF-α (pg/mL)	< 30	602.4 (96.1-3920.1)	0.001
TNF-α after LPS (pg/mL)	1693 (1185-3709)	2904 (931-5078)	0.150
TNF-α after LTA (pg/mL)	638.3 (49.7-1958)	2440 (241-4798)	0.006
Spontaneous IL-6 (pg/mL)	< 10	1537.8 (172.0-26053.9)	0.001
IL-6 after LPS (pg/mL)	20493 (19499-23042)	30219 (1362-32680)	0.006
IL-6 after LTA (pg/mL)	22157 (17390-27010)	30165 (3269-32707)	0.005
Spontaneous IL-10 (pg/mL)	< 30	43.6 (6.5-318.1)	0.210
IL-10 after LPS (pg/mL)	1309 (590.2-1578)	939.9 (120.8-2100)	0.890
IL-10 after LTA (pg/mL)	499.3 (268.7-816.9)	800.4 (80.72-2077)	0.150

TNF-α: Tumour necrosis factor-alpha; LPS: Lipopolysaccharide; LTA: Lipoteichoic acid; IL: Interleukin.