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. 2014 Dec 1;414:58–64. doi: 10.1016/j.jim.2014.07.012

Fig. 1.

Fig. 1

Foxp3 expression can be induced in antigen-specific Tconv cells with peptide, even when at low frequency. Tg4 CD45.1+ naive CD4+ T cells were titrated down among B10.PL (CD45.2+) naive T cells (from 100 down to 0.001% TCR-transgenic) before Foxp3 induction by activation with MBP Ac1-9 (1 μg/ml) in the presence of IL-2 and TGF-β1. Plots gated on live CD45.1+ cells on day 7 of differentiation culture. 1 experiment representative of 3 is shown.