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. 2015 Jan 1;5(1):23–42. doi: 10.7150/thno.10202

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Aptamer-guided theranostic nanomedicine. (A) Schematic representation of aptamer-associated theranostic nanomedicine. (B) Schematic illustration of the novel activatable theranostic nanoprobe (ATNP) strategy for aptamer-mediated imaging-guided photothermal therapy (PTT) in vivo. (C) In vivo aptamer-related activatable fluorescence imaging (a) and imaging-guided site-specific NIR PTT (b) of SPCAi (cyan circles) and A549 (pink circles) tumor following ATNP administration. Reproduced from Ref. 193, Copyright (2014), with permission from The Royal Society of Chemistry.