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. 2015 Jan 1;5(1):62–70. doi: 10.7150/thno.10145

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Detection of subtype of NSCLC tissue lysates, where we choose well-differentially Ade and SCC tissues due to their high similarity to normal epithelium under a microscope. (a) Change in absorption intensities for three different tissue lysates (normal, Ade and SCC) using the ssDNA-AuNPs-GO sensor array (NP1-NP6). (b) Heat map derived from absorbance response pattern for three human tissue lysates. (c) Canonical score plot for the two factors of absorbance response patterns against human tissue lysates, with 95% confidence ellipses. The canonical scores are calculated by LDA for the identification of three tissue lysates.