Table 2.

Copy numbers analysis by MLPA and MNPs-CL system.

	Gene	Meana ± SDb				Expected ratios of copy numbers
		Male	Female	Normal	Trisomy 21
MLPA	PCDH19	0.54 ± 0.06	0.99 ± 0.04			1:2
	RSK4	0.75 ± 0.05	0.95 ± 0.02			1:2
	SRY	0.48 ± 0.05	0			1:0
	DAZ1	0.42 ± 0.02	0			1:0
	DSCR3			0.79 ± 0.04	1.81 ± 0.09	2:3
	DSCR4			0.94 ± 0.08	1.37 ± 0.06	2:3
MNPs-CL	PCDH19	0.60 ± 0.02	0.99 ± 0.14			1:2
	RSK4	0.58 ± 0.02	0.90 ± 0.01			1:2
	SRY	0.55 ± 0.08	0			1:0
	DAZ1	0.52 ± 0.03	0			1:0
	DSCR3			0.96 ± 0.02	1.38 ± 0.11	2:3
	DSCR4			0.82 ± 0.05	1.32 ± 0.02	2:3

a Mean ratio to the reference normalized values with the averages of duplicate in 10 samples.

b Standard Deviation.