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. 2015 Jan 1;5(1):97–109. doi: 10.7150/thno.10298

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Burst destruction of intranodal microbubbles. After visualization of unloaded microbubble drainage, the scanner's burst function was used to destroy the microbubbles within the lymphatics. Images show (A) CEUS image with a ROI drawn around a lymph node filled with mRNA-loaded microbubbles and (B) the corresponding B-mode image. Burst analysis is represented in (C) as the echo mean (dB), where each burst is visible as an echo mean peak, followed by a reduction of the contrast echo mean. Time after mRNA-loaded microbubble injection is noted on the CEUS images (in min:s).