Table 2.
Baseline Characteristics by BMI Quartiles
| BMI Q1 (<21.8) (N = 254) |
BMI Q2 (21.8–25.0) (N = 248) |
BMI Q3 (25.1–28.7) (N = 238) |
BMI Q4 (>28.7) (N = 260) |
P Value* | |
|---|---|---|---|---|---|
| BMI (kg/m2) | 19.7 ± 1.6 | 23.3 ± 0.9 | 26.8 ± 1.0 | 32.9 ± 3.9 | |
| Serum creatinine (mg/dL) | 10.2 ± 3.0 | 10.5 ± 2.9 | 10.7 ± 3.1 | 10.4 ± 2.7 | .23 |
| Demographics | |||||
| Age (y) | 53 ± 16 | 56 ± 14 | 59 ± 12 | 59 ± 12 | <.001 |
| Male gender | 56% | 48% | 56% | 69% | <.001 |
| Black race | 69% | 64% | 73% | 64% | .14 |
| Dialysis characteristics | |||||
| HEMO high Kt/V group | 49% | 48% | 46% | 52% | .54 |
| HEMO high-flux group | 49% | 53% | 46% | 53% | .33 |
| Dialysis vintage (y) | 2.6 ± 3.7 | 3.6 ± 4.7 | 3.7 ± 4.2 | 3.7 ± 4.1 | .01 |
| Comorbidity | |||||
| Diabetes | 28% | 36% | 50% | 59% | <.001 |
| Congestive heart failure | 50% | 50% | 48% | 49% | .97 |
| Arrhythmias and conduction defects | 42% | 44% | 41% | 40% | .82 |
| Ischemic and other heart disease | 83% | 78% | 77% | 83% | .18 |
| Cerebral and peripheral vascular disease | 41% | 46% | 41% | 45% | .49 |
| Gastrointestinal disease | 61% | 61% | 56% | 59% | .60 |
| Respiratory disease | 22% | 18% | 16% | 24% | .10 |
| Nonvascular nervous system disease | 50% | 50% | 44% | 52% | .25 |
| Malignancy | 10% | 11% | 8% | 12% | .69 |
| Laboratory data | |||||
| Log CRP (mg/L) | 3.0 ± 0.8 | 2.9 ± 0.7 | 2.9 ± 0.7 | 3.0 ± 0.7 | .30 |
| Serum albumin (g/dL) | 3.6 ± 0.5 | 3.6 ± 0.5 | 3.6 ± 0.4 | 3.5 ± 0.4 | .08 |
| Serum bicarbonate (mEq/L) | 20.9 ± 4.7 | 21.1 ± 4.1 | 21.1 ± 3.9 | 21.4 ± 3.6 | .66 |
Q, quartile; BMI, body mass index; HEMO, Hemodialysis Study; CRP, C-reactive protein.
*
P values calculated by ANOVA for continuous variables and Cochran-Mantel-Haenszel tests.