Figure 11. Coinfected animals have a significantly increased number of FoxP3⁺ T regulatory cells.

Cells were isolated from the lungs of singly or coinfected mice on d8 post-influenza virus infection. T regulatory cells were detected based on positivity for CD4, CD25, and FoxP3. Data are the average of 9 influenza infected or 7 coinfected mice assessed across two independent experiments. A two tailed student’s t test was used to determine significance. * p<0.05