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(A), (B): Western blot analysis of C225, IgG-AuNPs or C225-AuNPs on levels of EGFR, Akt, phospho-Akt, ERK, phospho-ERK and Bcl-2 in EGFR-high expressing A549 cells. (C), (D): Western blot analysis of C225, IgG-AuNPs or C225-AuNPs on levels of membranous and cytoplasmic EGFR in A549 cells. β-actin serves as a loading control. The results shown are representative of three independent experiments. Values represent the mean ± SD. (**p < 0.01; *p < 0.05).
