Table 2.
Treatment characteristics
| Patient no. | Sonication target and side | Final temperature (°C) | Global symptom relief 3 months (%) | Pre-FUS UPDRS I/II/III/IV (max. 16/52/56/23, total 147) | 3 months post-FUS UPDRS I/II/III/IV (max. 16/52/56/23, total 147) | Pre-FUS MMST (max. 30) | 3 months post-FUS MMST (max. 30) | Pre-FUS HADS (max. 42) | 3 months post-FUS HADS (max. 42) | |
|---|---|---|---|---|---|---|---|---|---|---|
| Group 1 |
1 |
PTT right |
52 |
0 |
0/2/3/6 |
2/11/5/7 |
29 |
30 |
17 |
20 |
| Total 11 |
Total 25 |
|||||||||
| 2 |
PTT right |
52 |
30 |
0/14/17/3 |
0/10/17/2 |
30 |
30 |
9 |
4 |
|
| Total 34 |
Total 29 |
|||||||||
| 3 |
PTT right |
57 |
40 |
0/18/29/4 |
1/20/24/2 |
29 |
29 |
12 |
18 |
|
| Total 51 |
Total 47 |
|||||||||
| 4 |
PTT right |
59 |
20 |
0/18/26/5 |
0/12/20/1 |
27 |
27 |
13 |
9 |
|
| Total 49 |
Total 33 |
|||||||||
| Group 2 |
5 |
PTT right |
59 |
50 |
0/5/18/5 |
0/1/7/0 |
30 |
30 |
5 |
9 |
| Total 28 |
Total 8 |
|||||||||
| 6 |
PTT left |
57 |
55 |
1/10/15/5 |
0/6/6/0 |
29 |
30 |
20 |
19 |
|
| Total 31 |
Total 12 |
|||||||||
| 7 |
PTT left |
57 |
80 |
4/21/20/6 |
1/12/2/4 |
30 |
30 |
13 |
14 |
|
| Total 51 |
Total 19 |
|||||||||
| 8 |
PTT right |
58 |
5 |
0/10/22/5 |
0/9/15/0 |
29 |
30 |
11 |
9 |
|
| Total 37 |
Total 24 |
|||||||||
| 9 |
PTT left |
57 |
50 |
4/17/19/10 |
1/5/2/4 |
30 |
29 |
34 |
26 |
|
| Total 50 |
Total 12 |
|||||||||
| 10 |
PTT right |
56 |
50 |
3/9/20/7 |
3/6/4/0 |
29 |
30 |
14 |
18 |
|
| Total 39 |
Total 13 |
|||||||||
| 11 |
PTT right |
56 |
80 |
0/19/29/4 |
2/9/13/0 |
30 |
29 |
12 |
3 |
|
| Total 53 |
Total 24 |
|||||||||
| 12 |
PTT right |
56 |
70 |
0/5/14/6 |
1/3/8/0 |
29 |
30 |
9 |
10 |
|
| Total 25 |
Total 12 |
|||||||||
| 13 |
PTT left |
54 |
70 |
3/22/11/8 |
3/4/9/0 |
26 |
28 |
14 |
10 |
|
| Total 44 |
Total 16 |
|||||||||
| Mean | - | 56.2 | - | - | - | 29 | 29.4 | 14.1 | 13 |
The treatment characteristics include the target and side and the mean and maximum temperatures achieved during treatment. The subjective 3-month follow-up global symptom relief, as well as the pre- and post-FUS UPDRS scores shown here, are also displayed on Figure 4. The pre- and post-operative Mini Mental State Test (MMST) scores as well as Hospital Anxiety and Depression Scores (HADS) on the last four rows show no cognition losses and no emotional worsening for both groups of patients.